EVALUATION OF LETHALITY CAUSED BY ACUTE POISONING WITH PSYCHOACTIVE DRUGS IN ELDERLY AND SENILE PATIENTS IN N.V. SKLIFOSOVSKY RESEARCH INSTITUTE FOR EMERGENCY MEDICINE DURING 2013–2015
https://doi.org/10.23934/2223-9022-2017-6-4-318-323
Abstract
We performed the clinical and morphological analysis of 84 elderly and senile patients, died of poisonings with psychoactive drugs in 2013–2015. There were two main drug agents: benzodiazepines and barbiturates. During the first 5 days intoxication was a cause of death in 15.5%, pneumonia — in 44%. The peak of mortality due to pneumonia was registered on week 3 and later in the presence of hypostasis. Morphological analysis showed various pathological findings in different lungs areas. Сirculation disorders, thrombosis, alternation of dystelectasis and emphysema, edema, atelectasis, bronchoconstriction, bronchiolitis and aerocele were detected out of pneumonic focuses. The most frequent abdominal pathological findings were liver and pancreatic steatosis. Prolonged toxic phase, crucial role of hypostasis in pneumonia incidence and the disease course on the background of acute and chronicle diseases were special aspects in this category of patients.
About the Authors
L. N. Zimina
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department
Russian Federation
Russian Federation
Professor, Dr. Med. Sci., Leading Researcher of the Department for Pathological Anatomy,
Moscow
M. V. Barinova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department
Russian Federation
Moscow
Russian Federation
Moscow
M. A. Polozov
Thanatological department №3, Bureau of Forensic Medicine, Ministry of Healthcare and Social Development
Russian Federation
Moscow
Russian Federation
Moscow
G. V. Mikhailova
Thanatological department №3, Bureau of Forensic Medicine, Ministry of Healthcare and Social Development
Russian Federation
Moscow
Russian Federation
Moscow
P. A. Rozumny
Thanatological department №3, Bureau of Forensic Medicine, Ministry of Healthcare and Social Development
Russian Federation
Moscow
Russian Federation
Moscow
G. Y. Sakharov
Thanatological department №3, Bureau of Forensic Medicine, Ministry of Healthcare and Social Development
Russian Federation
Moscow
Russian Federation
Moscow
V. A. Strokov
Thanatological department №3, Bureau of Forensic Medicine, Ministry of Healthcare and Social Development
Russian Federation
Moscow
Russian Federation
Moscow
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For citations:
Zimina L.N., Barinova M.V., Polozov M.A., Mikhailova G.V., Rozumny P.A., Sakharov G.Y., Strokov V.A. EVALUATION OF LETHALITY CAUSED BY ACUTE POISONING WITH PSYCHOACTIVE DRUGS IN ELDERLY AND SENILE PATIENTS IN N.V. SKLIFOSOVSKY RESEARCH INSTITUTE FOR EMERGENCY MEDICINE DURING 2013–2015. Russian Sklifosovsky Journal "Emergency Medical Care". 2017;6(4):318-323. (In Russ.) https://doi.org/10.23934/2223-9022-2017-6-4-318-323
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