Combined Treatment of Giant Extra-Intracranial Arteriovenous Malformation
V. A. Lukyanchikov,
V. A. Dalibaldyan,
S. Yu. Roschin,
I. I. Goncharova,
G. K. Guseynova,
S. V. Zhuravel,
V. A. Karanadze,
A. S. Koblik,
V. E. Ryabukhin,
A. V. Sachkov,
A. A. Grin,
V. V. Krylov https://doi.org/10.23934/2223-9022-2025-14-1-203-215
Abstract
Arteriovenous malformations are formations consisting of dysplastic, dilated blood vessels in which blood, bypassing the capillary network, enters the venous bed and causes significant expansion of the veins. In addition, arteriovenous malformations can cause nutritional disorders (trophism) of the soft tissues located near them. Extracranial arteriovenous malformations are rare and dangerous vascular anomalies. At present, there are no universal algorithms for their treatment. This article presents the experience of surgical combined treatment of a patient with extracranial arteriovenous malformation. First, staged endovascular occlusion of the formation was performed , and then its complete removal in a hybrid operating room. This approach allowed performing a radical intervention with a positive result.
About the Authors
V. A. Lukyanchikov
N.V. Sklifosovsky Research Institute of Emergency Medicine; N.I. Pirogov Russian National Research Medical University (Pirogov University)
Russian Federation
Russian Federation
Viktor A. Lukyanchikov - Doctor of Medical Sciences, Professor of the Department of Fundamental Neurosurgery, N.I. Pirogov Russian National Research Medical University (Pirogov University); Leading Researcher of the Second Neurosurgical Department, Scientific Center of Neurology, Researcher of the Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090; Ostrovityanova Str. 1, Moscow, 117513
V. A. Dalibaldyan
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Vagan A. Dalibaldyan - Candidate of Medical Sciences, Neurosurgeon, Senior Researcher of Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
S. Yu. Roschin
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Stanislav Yu. Rosсhin - Neurosurgeon, Junior Researcher of the Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
I. I. Goncharova
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Irina I. Goncharova - Candidate of Medical Sciences, Senior Researcher, Anesthesiology Department No. 1, Anesthesiologist-Resuscitator, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
G. K. Guseynova
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Gyul’nara K. Guseynova - Ultrasound Diagnostics Doctor, Researcher at the Department of Radiation Diagnostics, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
S. V. Zhuravel
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Sergey V. Zhuravel - Doctor of Medical Sciences, Head of the Scientific Department of Anesthesiology No. 1, 3; Anesthesiologist-Resuscitator, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
V. A. Karanadze
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Vasily A. Karanadze - Candidate of Medical Sciences, Head of the Department of Neurosurgery for the Treatment of Patients with Vascular Diseases of the Brain, Researcher of the Department of Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
A. S. Koblik
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Aleksandra S. Koblik - Doctor of X-ray Endovascular Diagnostic and Treatment Methods, Junior Researcher, Department of X-ray Surgical Diagnostic and Treatment Methods, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
V. E. Ryabukhin
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Vitaliy E. Ryabukhin - Candidate of Medical Sciences, Senior Researcher, Department of X-ray Surgical Diagnostic and Treatment Methods, Physician of X-ray Endovascular Diagnostics and Treatment, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
A. V. Sachkov
N.V. Sklifosovsky Research Institute of Emergency Medicine
Russian Federation
Russian Federation
Aleksey V. Sachkov - Candidate of Medical Sciences, Head of the Scientific Department of Acute Thermal Injuries, Surgeon, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090
A. A. Grin
N.V. Sklifosovsky Research Institute of Emergency Medicine; N.I. Pirogov Russian National Research Medical University (Pirogov University)
Russian Federation
Russian Federation
Andrey A. Grin - Corresponding Member of the RAS, Doctor of Medical Sciences, Professor of the Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University (Pirogov University), Head of the Scientific Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090; Ostrovityanova Str. 1, Moscow, 117513
V. V. Krylov
N.V. Sklifosovsky Research Institute of Emergency Medicine; N.I. Pirogov Russian National Research Medical University (Pirogov University)
Russian Federation
Russian Federation
Vladimir V. Krylov - Academician of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Head of the Department of Fundamental Neurosurgery, Pirogov Russian National Research Medical University (Pirogov University); Chief Researcher, Department of Emergency Neurosurgery, N.V. Sklifosovsky Research Institute for Emergency Medicine.
Bolshaya Sukharevskaya Sq. 3, Moscow, 129090; Ostrovityanova Str. 1, Moscow, 117513
References
1. Liu AS, Mulliken JB, Zurakowski D, Fishman SJ, Greene AK. Extracranial arteriovenous malformations: natural progression and recurrence after treatment. Plast Reconstr Surg. 2010;125(4):1185–1194. PMID: 20335868 https://doi.org/10.1097/PRS.0b013e3181d18070
2. Derdeyn CP, Zipfel GJ, Albuquerque FC, Cooke DL, Feldmann E, Sheehan JP, et al. Management of Brain Arteriovenous Malformations: A Scientific Statement for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke. 2017;48(8):e200–e224. PMID: 28642352 https://doi.org/10.1161/STR.0000000000000134
3. Ondra SL, Troupp H, George ED, Schwab K. The Natural History of Symptomatic Arteriovenous Malformations of the Brain: A 24-Year Follow-Up Assessment. J Neurosurg. 1990;73(3):387–391. PMID: 2384776 https://doi.org/10.3171/jns.1990.73.3.0387
4. Kohout MP, Hansen M, Pribaz JJ, Mulliken JB. Arteriovenous malformations of the head and neck: natural history and management. Plast Reconstr Surg. 1998;102(3):643–654. PMID: 9727427 https://doi.org/10.1097/00006534-199809030-00006
5. Hsu YC, Huang SY, Chou CM. Giant congenital arteriovenous malformation over right upper limb causing heart failure. Asian J Surg. 2020;43(10):1016–1017. PMID: 32653151 https://doi.org/10.1016/j.asjsur.2020.05.035
6. Lilje D, Wiesmann M, Hasan D, Ridwan H, Hölzle F, Nikoubashman O. Interventional embolization combined with surgical resection for treatment of extracranial AVM of the head and neck: A monocentric retrospective analysis. PLoS One. 2022;17(9): e0273018. PMID: 36048777 https://doi.org/10.1371/journal.pone.0273018 eCollection 2022.
7. Zou Y, Qiao C, Lin X, Jin Y, Hua C, Yang X, et al. Clinical Course of Extracranial Arteriovenous Malformations. J Craniofac Surg. 2020;31(2):372–376. PMID: 31764560 https://doi.org/10.1097/SCS.0000000000006018
8. Lilje D, Wiesmann M, Hasan D, Riabikin A, Ridwan H, Ho¨lzle F, et al. Interventional therapy of extracranial arteriovenous malformations of the head and neck-A systematic review. PLoS One. 2022;17(7): e0268809. PMID: 35839171 https://doi.org/10.1371/journal.pone.0268809 eCollection 2022.
9. Mohr JP, Parides MK, Stapf C, Moquete E, Moy CS, Overbey JR, et al.; International ARUBA investigators. Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. Lancet. 2014;383(9917):614–621. PMID: 24268105 https://doi.org/10.1016/S0140-6736(13)62302-8
10. Folkman J. Angiogenesis: An organizing principle for drug discovery? Nat Rev Drug Discov. 2007;6(4):273–286. PMID: 17396134 https://doi.org/10.1038/nrd2115
Review
For citations:
Lukyanchikov V.A., Dalibaldyan V.A., Roschin S.Yu., Goncharova I.I., Guseynova G.K., Zhuravel S.V., Karanadze V.A., Koblik A.S., Ryabukhin V.E., Sachkov A.V., Grin A.A., Krylov V.V. Combined Treatment of Giant Extra-Intracranial Arteriovenous Malformation. Russian Sklifosovsky Journal "Emergency Medical Care". 2025;14(1):203-215. (In Russ.) https://doi.org/10.23934/2223-9022-2025-14-1-203-215
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