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SYSTEMIC THROMBOLYSIS FOR TREATMENT OF ACUTE LIMB ISCHEMIA

Abstract

ABSTRACT. Treatment of acute limb ischemia remains a serious problem in vascular surgery. There are both surgical and conservative therapies. Systemic thrombolysis is one of supplementing methods, and in some cases, it is the method of choice, especially when surgical therapy is not possible. The paper presents our experience of systemic thrombolytic therapy in the treatment of acute limb ischemia. 

About the Authors

I. P. Mikhaylov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation


G. A. Isayev
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation


L. S. Kokov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation


V. Y. Shestoperov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation


V. N. Lavrenov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation


References

1. Berridge D., Kessel D., Robertson I. Surgery versus thrombolysis for initial management of acute limb ischaemia // Cochrane Database Syst. Rev. – 2002. – N. 3. – CD002784.

2. Kropman R.H., Schrijver A.M., Kelder J.C., et al. Clinical outcome of acute leg ischaemia due to thrombosed popliteal artery aneurysm: systematic review of 895 cases // Eur. J. Vasc. Endovasc. Surg. – 2010. – Vol. 39, N. 4. – Р. 452–457.

3. Limtungturakul S., Wongpraparut N., Pornratanarangsri S., et al. Early experience of catheter directed thrombolysis for acute limb ischemia of native vessels and bypass graft thrombosis in Thai patients // J. Med Assoc. Thai. – 2011. – Vol. 94, Suppl. 1. – S11–S18.

4. Ouriel K., Veith F.J., Sasahara A.A. A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators // N. Engl. J. Med. – 1998. –Vol. 338, N. 16. – P. 1105–1111.


Review

For citations:


Mikhaylov I.P., Isayev G.A., Kokov L.S., Shestoperov V.Y., Lavrenov V.N. SYSTEMIC THROMBOLYSIS FOR TREATMENT OF ACUTE LIMB ISCHEMIA. Russian Sklifosovsky Journal "Emergency Medical Care". 2015;(2):32-34.

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ISSN 2223-9022 (Print)
ISSN 2541-8017 (Online)