Extremely High-frequency Therapy in the Complex Treatment of Pneumonia in Patients with Burn and Inhalation Trauma

Background. The improvement of treatment tactics for nosocomial pneumonia in patients with burn and inhalation trauma is a relevant issue due to the frequency of this complication, which develops at any stage of treatment and aggravates the course of the underlying disease.

Aim of study. To evaluate the effectiveness of extremely high frequency therapy (EHFT) in the complex treatment of pneumonia in patients with burn and inhalation injury.

Material and methods. The results of extremely high-frequency therapy (EHFT) was compared, studying 23 burn patients with complex EHFT and 30 patients without EHFT.

Results. EHFT reduces the signs of endogenous toxemia, as evidenced by a statistically significant decrease in elevated concentrations of dead leukocytes in venous blood from 147-10⁶/L (98; 363-10⁶/L) to 81.8-10⁶/L (72; 150-10⁶/L) (p=0.041, Wilcoxon test) on day 6-8 (after 5-6 procedures), whereas in the comparison group, on the contrary, an increase in the dead cells from 121-10⁶/L (66; 210-10⁶/L) up to 137.4-10⁶/L (116; 207-10⁶/L) was observed. When comparing this indicator in two groups on day 6-8 from the onset of pneumonia, a statistically significant difference was found (p=0.021, Mann-Whitney). The term of managing pneumonia in patients receiving EHFT was significantly shorter than in the comparison group, 18 (13; 23) versus 21 (18; 27) days (p=0.020, Mann-Whitney).

Conclusion. EHFT reduced intensity of endogenous toxicosis and inflammation, approaching pneumonia relief for 3 days.

1. Onctil О., Okstiz S., Acar А., et al. Nosocomial infection characteristics in a burn intensive care unit: analysis of an eleven-year active surveillance. Burns. 2014; 40 (5): 835-841. PMID: 24296064. DOI: 10.1016/j.burns.2013.11.003.

2. Pham T.N., Kramer C.B., Klein M.B. Risk factors for the development of pneumonia in older adults with burn injury. JBurn Care Res. 2010; 31(1): 105-110. DOI: 10.1097/BCR.0b013e3181cb8c5a.

3. Rogers A.D. Argent A.C., Rode H. Review article: ventilator-associated pneumonia in major burns. Ann Burns and Fire Disasters. 2012; 25(3): 135139. PMID: 23467023.

4. Dries, D.J. Management of burn injuries — recent developments in resuscitation, infection control and outcomes research. Scand J Trauma Resusc EmergMed. 2009; 17(1): 14. PMID: 19284591. DOI: 10.1186/1757-7241-17-14.

5. Mgahed M., El-Helbawy R, Omar A., et al. Early detection of pneumonia as a risk factor for mortality in burn patients in Menoufiya University Hospitals, Egypt. Ann Burns and Fire Disasters. 2013; 26(3): 128-135. PMID: 24563638.

6. Hussain A., Dunn K. Burn related mortality in Greater Manchester: 11-year review of Regional Coronial Department Data. Burns. 2014; 41(2): 225234. PMID: 25468472. DOI:10.1016/j.burns.2014.10.008.

7. Rue L.W., Cioffi W.G., Mason A.D., et al. Improved survival of burned pa-tients with inhalation injury. Arch Surg. 1993; 128(7): 772-778. PMID: 8317959.

8. Vagina I.L., Khelminskaya N.M., Istomina I.S, et al. The evaluation of effectiveness of application of extremely high frequencies and extremely high frequencieslaser combined effect in complex treatment of patients with pyoinflammatory diseases of maxillo-facial area. Rossiyskiy meditsinskiyzhurnal. 2014; (2): 23-26. (In Russian).

9. Istomina I.S. EHF therapy in clinical practice (Part II). Fizioterapiya, bal’neologiya i reabilitatsiya. 2012; (6): 38-45. (In Russian).

10. Istomina I.S. EHF therapy in clinical practice (Part I). Fizioterapiya, bal’neologiya i reabilitatsiya. 2012; (2): 47-52. (In Russian).

11. Betskiy O.V., Kislov V.V., Lebedeva N.N. Millimeter waves and living systems. Moscow: SAYNS-PRESS Publ., 2004. 272 p. (In Russian).

12. Shchelkunova I.G. Effect of millimeter therapy on hemostasis and rheological properties of blood in patients with unstable angina: Cand. med. sci. diss. synopsis. Moscow, 1996. 25 p. (In Russian).

13. Kirichuk V.F., Malinova L.I., Krenitskiy A.P. Hemorheology and electromagnetic EHF radiation. Saratov: SGMU Publ., 2003. 190 p. (In Russian).

14. Briskin B.S., et al. Millimeter waves and their application in the treatment of acute pancreatitis. Moscow: MGMSU Publ., 2005. 69 p. (In Russian).

15. Poslavskiy M.V, Korotkiy I.M., Golant M.B., et al. The use of electromagnetic waves of the millimeter-wave range for the treatment and prevention of gastric ulcer and duodenal ulcer. In: Methodical recommendations on millimeter (extremely high frequency) therapy. Moscow: MTA KVCH Publ., 2007: 5-18. (In Russian).

16. Khomenko A.G., Chukanov V.I., Kaminskaya G.O., et al. The use of millimeter waves in the complex treatment of patients with pulmonary tuberculosis. Moscow, 1995. 22 p. (In Russian).

17. Gedymin L.E., KHomenko A.G., Novikova YA.N., Golant M.B. Experimental and clinical use of EHF-therapy in the clinic of pulmonary diseases. Millimetrovyyevolny v biologii i meditsine. 1998; (2): 36. (In Russian).

18. Borisova S.B. Treatment of patients with sarcoidosis of respiratory organs by electromagnetic waves of millimeter range with noise radiation: Cand. med. sci. diss. synopsis. Nizhny Novgorod, 2005. 25p. (In Russian).

19. Skripal’ A.Yu. Diagnostic and therapeutic fiber-optic bronchoscopy with burns of the respiratory tract: Cand. med. sci. diss. synopsis. Moscow, 1990. 24p. (In Russian).