AGE-RELATED CHANGES OF HEMORHEOLOGICAL STATUS
Abstract
ABSTRACT. The paper presents the results of hemorheological parameters and coagulation study in 67 volunteers of three age groups, including young, middle-aged and elderly people. Studies have shown that values of the vast number of blood rheological parameters increase with advancing age, which is mostly significant after 60 years. Based on the findings, it is concluded that the presented results of hemorheological parameters studies in patients older than 60 years should be used as a comparison group in evaluation of the disease severity and the effectiveness of treatment for geriatric patients.
About the Authors
E. E. Bitkova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation
Russian Federation
K. K. Ilyashenko
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation
Russian Federation
V. B. Khvatov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation
Russian Federation
A. Yu. Simonova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow
Russian Federation
Russian Federation
References
1. Борисов В. Демографическая ситуация в современной России / В. Борисов // Демографические исследования. – 2006. – № 1. – С. 13–15. Borisov V. Demograficheskaya situatsiya v sovremennoy Rossii [The demographic situation in modern Russia]. Demograficheskie issledovaniya. 2006; 1: 13–15. (In Russian).
2. Feher G., Koltai K., Kesmarky G., et al. Hemorheological parameters and aging // Clin. Hemorheol. Microcirc. – 2006. – Vol. 35, N. 1–2. – P. 89–98.
3. Feher G., Koltai K., Toth K. Are hemorheological parameters independent of aging? // Clin. Hemorheol. Microcirc. – 2007. – Vol. 36, N. 2. – P. 181–182.
4. Simmonds M.J., Meiselman H.J., Baskurt O.K. Blood rheology and aging // J. Geriatr. Cardiol. – 2013. – Vol. 10, N. 3. – P. 291–301.
5. Whittaker S.R., Winton F.R. The apparent viscosity of blood flowing in the isolated hindlimb of the dog and its variation with corpuscular concentration // J. Physiol. – 1933. – Vol. 78, N. 4. – P. 339–368.
6. Dintenfass L. Blood rheology in pathogenesis of the coronary heart diseases // Am. Heart J. – 1969. – Vol. 77, N. 1. – P. 139–147.
7. Brown M.M., Marshall J. Effect of plasma exchange on blood viscosity and cerebral blood flow // Br. Med. J. (Clin. Res. Ed). – 1982. – Vol. 12, N. 284 (6331). – P. 1733–1736.
8. Wood J.H., Kee D.B. Jr. Hemorheology of the cerebral circulation in stroke // Stroke. – 1985. – Vol. 16, N. 5. – P. 765–772.
9. Dintenfass, L. The cause of death: blood hyperviscosity? // J. R. Soc. Med. – 1987. - Vol. 80, N. 8. – P. 536–537.
10. DeFilippis A.P., Law K., Curtin S., Eckman J.R. Blood is thicker than water: the management of hyperviscosity in adults with cyanotic heart disease // Cardiol. Rev. – 2007. – Vol. 15, N. 1. – P. 31–34.
11. Исследование системы крови в клинической практике / под ред. Г.И. Козинца, В.А. Макарова. – М.: Триада-Х, 1998. – 480 с. Kozints G.I., Makarova V.A., ed. Issledovanie sistemy krovi v klinicheskoy praktike [The study of the blood system in clinical practice]. Moscow: Triada-X Publ., 1998. 480 p. (In Russian).
12. Сапари Л., Хорват Б., Алекси Т. и др. Влияние кавинтона на реологические свойства крови у больных с хронической цереброваскулярной недостаточностью // Журнал неврологии и психиатрии. – 2006. – №6. – С. 47–51. Sapari L., Khorvat B., Aleksi T., et al. Vliyanie kavintona na reologicheskie svoystva krovi u bol’nykh s khronicheskoy tserebrovaskulyarnoy nedostatochnost’yu [Influence Cavinton on the rheological properties of blood in patients with chronic cerebrovascular insufficiency]. Zhurnal nevrologii i psikhiatrii. 2006; 6: 47–51. (In Russian).
13. Baskurt O.K., Meiselman H.J. Iiatrogenic hyperviscosity and thrombosis // Semin. Thromb. Hemost. – 2012. – Vol. 38, N. 8. – P. 854–864.
14. Li R.Y., Cao Z.G., Li Y., Wang R.T. Increased whole blood viscosity is associated with silent cerebral infarction // Clin. Hemorheol. Microcirc. – 2015. – Vol. 59, N. 4. – P. 301–307.
15. Zhao H.Y., Li J., Xu M., et al. Elevated whole blood viscosity is associated with insulin resistance and non-alcoholic fatty liver // Clin Endocrinol (Oxf). – 2015, Mar 30. [Epub ahead of print].
16. Leschke M. Rheology and coronary heart disease // Dtsch. Med. Wochenschr. – 2008. – Vol. 133, Suppl. 8. – P. S270–273.
17. Caprari P., Tarzia A., Mojoli G., et al. Hereditary spherocytosis and elliptocytosis associated with prosthetic heart valve replacement: rheological study of erythrocyte modifications // Int. J. Hematol. – 2009. – Vol. 89, N. 3. – P. 285–293.
18. Richards P.D., Richards A.A., McKoy M.G., Pepple D.J. The in vitro effects of sulfadoxine/pyrimethamine and artemether/lumefantrine on the viscoelasticity of erythrocyte membrane of healthy females // lin. Hemorheol. Microcirc. – 2014. – Vol. 58, N. 4. – P. 507–514.
19. Hagley A.C., Younger¬Coleman N.O., Richards A.A. The effect of sildenafil on the elasticity of erythrocytes in homozygous sickle cell disease // Indian. J. Med. Sci. – 2011. – Vol. 65, N. 6. – P. 243–249.
20. Glass G.A., Gershon D., Gershon H. Some characteristics of the humanerythrocyte as a function of donor and cell age // Exp. Hematol. – 1985. – Vol. 13, N. 11. – P. 1122–1126.
21. Pinkofsky H.B. The effect of donor age on human erythrocyte density distribution // Mech. Age Dev. – 1997. – Vol. 97, N. 1. – P. 73–79.
22. Rosencranz R., Bogen S.A. Clinical laboratory measurement of serum, plasma, and blood viscosity // Am. J. Clin. Pathol. – 2006. – Vol. 125, Suppl. – S78–S86.
Review
For citations:
Bitkova E.E., Ilyashenko K.K., Khvatov V.B., Simonova A.Yu. AGE-RELATED CHANGES OF HEMORHEOLOGICAL STATUS. Russian Sklifosovsky Journal "Emergency Medical Care". 2015;(4):27-29.
Views:
708
Email this article 