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Coronary Arteries Spasm After Administration of Atropine for Premedication

https://doi.org/10.23934/2223-9022-2024-13-2-299-304

Abstract

   We report a case of severe retrosternal pain in 28-year-old patient with no cardiovascular diseases in history, developed after intravenous administration of 0.5 atropine sulfate 0.1 % solution for the purpose of premedication before the planned operation for endometrioid ovarian cysts and managed with nitrates spray. Taking into account the clinical picture, transient ischemic changes in the electrocardiogram and the association with the administration of atropine, it can be assumed that the patient had a spasm of the coronary arteries caused by the administration of atropine. There are only a very small number of descriptions of similar observations in the literature, which are also discussed in the article.

About the Authors

A. Yu. Shchedrina
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Anna Yu. Shchedrina, Candidate of Medical Sciences, Head of the Department

Cardiology Center; Department of Geriatric Cardiology

129226; 1-st Leonova Str. 16; Moscow



A. Z. Khashukoeva
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Asiyat Z. Khashukoeva, Doctor of Medical Sciences, Professor

Cardiology Center; Department of Obstetrics and Gynecology

129226; 1-st Leonova Str. 16; Moscow



L. P. Prokhorova
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Lyubov P. Prokhorova, Obstetrician-gynecologist

Cardiology Center; Gynecology Department

129226; 1-st Leonova Str. 16; Moscow



K. A. Eruslanova
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Kseniia A. Eruslanova, Candidate of Medical Sciences, Head of the Laboratory

Cardiology Center; Laboratory of Cardiovascular Aging

129226; 1-st Leonova Str. 16; Moscow



E. A. Rodnyanskaya
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Ekaterina A. Rodnyanskaya, Anesthesiologist and Resuscitator

Cardiology Center; Department of Anesthesiology and Resuscitation

129226; 1-st Leonova Str. 16; Moscow



A. M. Shatov
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Aleksey M. Shatov, Anesthesiologist and Resuscitator

Cardiology Center; Department of Anesthesiology and Resuscitation

129226; 1-st Leonova Str. 16; Moscow



A. F. Farzutdinov
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Artur F. Farzutdinov, Head of the Department, Anesthesiologist and Resuscitator

Cardiology Center; Department of Anesthesiology-Resuscitation and Intensive Care

129226; 1-st Leonova Str. 16; Moscow



N. F. Fathi
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Nina F. Fathi, Anesthesiologist and Resuscitator

Cardiology Center; Department of Anesthesiology and Resuscitation

129226; 1-st Leonova Str. 16; Moscow



M. A. Fedin
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Maksim A. Fedin, Cardiologist

Cardiology Center; Department of Geriatric Cardiology

129226; 1-st Leonova Str. 16; Moscow



K. O. Orunbekova
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Kunduz O. Orunbekova, Resident

Cardiology Center

129226; 1-st Leonova Str. 16; Moscow



O. N. Tkacheva
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Olga N. Tkacheva, Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Director of the Center

Cardiology Center

129226; 1-st Leonova Str. 16; Moscow



S. R. Gilyarevsky
N.I. Pirogov Russian National Research Medical University, Russian Gerontological Research and Clinical Center
Russian Federation

Sergey R. Gilyarevsky, Head of the Center

Cardiology Center

129226; 1-st Leonova Str. 16; Moscow



References

1. Lee JH, Seok JH, Kim YL, Lee JH, Lee SG, Kim EJ, et al. Atropine injection followed by coronary artery spasm with ventricular tachycardia during spinal anesthesia. A case report. Korean J Anesthesiol. 2013;65(1):66–70. PMID: 23904942 doi: 10.4097/kjae.2013.65.1.66

2. Castellano-Martinez A, Rodriguez-Gonzalez M. Coronary artery spasm due to intravenous atropine infusion in a child: possible Kounis syndrome. Cardiol Young. 2018;28(4):616–618. PMID: 29316984 doi: 10.1017/S1047951117002785

3. Averill KH, Lamb LE. Less commonly recognized actions of atropine on cardiac rhythm. Am J Med Sci. 1959;237(3):304–318 passim. PMID: 13626971 doi: 10.1097/00000441-195903000-00004

4. Hachisuka M, Fujimoto Y, Oka E, Hayashi H, Yamamoto T, Murata H, et al. Perioperative coronary artery spasms in patients undergoing catheter ablation of atrial fibrillation. J Interv Card Electrophysiol. 2022;64(1):77–83. PMID: 34773218 doi: 10.1007/s10840-021-01089-6


Review

For citations:


Shchedrina A.Yu., Khashukoeva A.Z., Prokhorova L.P., Eruslanova K.A., Rodnyanskaya E.A., Shatov A.M., Farzutdinov A.F., Fathi N.F., Fedin M.A., Orunbekova K.O., Tkacheva O.N., Gilyarevsky S.R. Coronary Arteries Spasm After Administration of Atropine for Premedication. Russian Sklifosovsky Journal "Emergency Medical Care". 2024;13(2):299-304. https://doi.org/10.23934/2223-9022-2024-13-2-299-304

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ISSN 2223-9022 (Print)
ISSN 2541-8017 (Online)