Hemlock (Conium Maculatum) Poisoning
https://doi.org/10.23934/2223-9022-2024-13-1-140-144
Abstract
Background Spotted hemlock (Conium maculatum) is one of the most poisonous plants. Hemlock poisoning is extremely rare, but can lead to serious consequences, including death.
Material and methods A clinical observation of a 50-year-old patient with a diagnosis of hemlock poisoning is presented.
Conclusion The clinical observation of acute hemlock poisoning presented by us does not exclude its direct cardiotoxic effect and requires further research in this direction, which will allow optimizing the treatment of this group of patients.
About the Authors
A. V. PoluninRussian Federation
Andrey V. Polunin - Toxicologist of the Intensive Care Unit for Emergency Detoxification.
3, Bolshaya Sukharevskaya Sq., Moscow 129090
A. Yu. Simonova
Russian Federation
Anastasia Yu. Simonova - Candidate of Medical Sciences, Leading Researcher of the Department of Acute Poisoning and Somatopsychiatric Disorders, N.V. Sklifosovsky RI for Emergency Medicine; Leading Researcher of the Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine; Acting Head of the Department of Clinical Toxicology, RMA for Continuous Professional Education.
3, Bolshaya Sukharevskaya Sq., Moscow 129090; 3 Bldg. 7, Bolshaya Sukharevskaya Sq., Moscow 129090; 2/1 Bldg. 1, Barrikadnaya Str., Moscow 125993
M. M. Potskhveriya
Russian Federation
Mikhail M. Potskhveriya - Doctor of Medical Sciences, Chief of the Department of Acute Poisoning and Somatopsychiatric Disorders, N.V. Sklifosovsky RI for Emergency Medicine; Professor of the Department of Clinical Toxicology, RMA for Continuous Professional Education.
3, Bolshaya Sukharevskaya Sq., Moscow 129090; 2/1 Bldg. 1, Barrikadnaya Str., Moscow 125993
K. K. Ilyashenko
Russian Federation
Kapitalina K. Ilyashenko - Doctor of Medical Sciences, Professor, Scientific Consultant of the Department of Acute Poisoning and Somatopsychiatric Disorders, N.V. Sklifosovsky RI for Emergency Medicine; Leading Researcher of the Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine.
3, Bolshaya Sukharevskaya Sq., Moscow 129090; 3 Bldg. 7, Bolshaya Sukharevskaya Sq., Moscow 129090
N. E. Stolbova
Russian Federation
Natalya E. Stolbova - Chief Physician.
3, Bolshaya Sukharevskaya Sq., Moscow 129090
M. V. Belova
Russian Federation
Maria V. Belova - Doctor of Biological Sciences, Leading Researcher of the Department of Acute Poisoning and Somatopsychiatric Disorders, N.V. Sklifosovsky RI for Emergency Medicine; Associate Professor of the Department of Clinical Toxicology, R MA for Continuous Professional Education.
3, Bolshaya Sukharevskaya Sq., Moscow 129090; 2/1 Bldg. 1, Barrikadnaya Str., Moscow 125993
T. T. Tkeshelashvili
Russian Federation
Tengiz T. Tkeshelashvili - Head of the Intensive Care Unit for Emergency Detoxification.
3, Bolshaya Sukharevskaya Sq., Moscow 129090
References
1. Hoffman RS, Nelson LS, Howland MA, Lewis NA, Flomenbaum NE, Goldfrank LR. (eds.) Goldfrank’s Manual of Toxicologic Emergencies. New York: McGrawHill Medical; 2007. (Russ. ed.: Khoffman R, Nel’son L, Khauland ME, L’yuin N, Flomenbaum N., Goldfrank L. Ekstrennaya meditsinskaya pomoshch’ pri otravleniyakh. Moscow: Praktika Publ.; 2010.)
2. Ilyashenko KK, Simonova AYu, Belova MV. A structural analysis of acute exotoxicoses in people of elderly and senile age. Toxicological Review. 2017;1(142):10–14. (In Russ.) https://doi.org/10.36946/08697922201711014
3. Belova MV, Ilyashenko KK, Simonova AYu, Potskhveriya MM, Trusov GV. The Structure of Acute Exotoxicosis During the First Three Months of the COVID19 Pandemic (According to the Acute Toxicosis Department of N.V. Sklifosovsky Research Institute for Emergency Medicine). Russian Sklifosovsky Journal Emergency Medical Care. 2021;10(1):27–32. https://doi.org/10.23934/2223902220211012732
4. Boskabadi J, Askari Z, Zakariaei Z, Fakhar M, Tabaripour R. Mildtosevere poisoning due to Conium maculatum as toxic herb: A case series. Clin Case Rep. 2021;9(7):e04509. PMID: 34322257 https://doi.org/10.1002/ccr3.4509
5. Karakasi MV, Tologkos S, Papadatou V, Raikos N, Lambropoulou M, Pavlidis P. Conium maculatum intoxication: literature review and case report on hemlock poisoning. Forensic Sci Rev. 2019;31(1):23–36. PMID: 30594904
6. West PL, Horowitz BZ, Montanaro MT, Lindsay JN. Poison hemlockinduced respiratory failure in a toddler. Pediatr Emerg Care. 2009;25(11):761–763. PMID: 19915429 https://doi.org/10.1097/PEC.0b013e3181bec925
7. Konca C, Kahramaner Z, Bosnak M, Kocamaz H. Hemlock (Conium maculatum) poisoning in a child. Turk J Emerg Med. 2014;14(1):34–36. PMID: 27331163 https://doi.org/10.5505/1304.7361.2013.23500
8. Brtalik D, Stopyra J, Hannum J. Intravenous poison hemlock injection resulting in prolonged respiratory failure and encephalopathy. J Med Toxicol. 2017;13(2):180–182. PMID: 28168558 https://doi.org/10.1007/s1318101706010
9. Ferah AU, Dilek MO, Ercument Y, Oktay D. Hemlock poisoning (case report): die like socrates. Resuscitation. 2006;70(2):337. https://doi.org/10.1016/j.resuscitation.2006.06.125
10. Grandhi RK, AbdElsayed A. Anticholinergics. Pharmacology in Clinical Neurosciences. Singapore: Springer; 2020. p. 165–171. https://doi.org/10.1007/9789811535918
Review
For citations:
Polunin A.V., Simonova A.Yu., Potskhveriya M.M., Ilyashenko K.K., Stolbova N.E., Belova M.V., Tkeshelashvili T.T. Hemlock (Conium Maculatum) Poisoning. Russian Sklifosovsky Journal "Emergency Medical Care". 2024;13(1):140-144. https://doi.org/10.23934/2223-9022-2024-13-1-140-144