The Role of Extracorporeal Membrane Oxygenation in the Complex Treatment of Acute Chemical Poisoning
https://doi.org/10.23934/2223-9022-2023-12-3-448-457
Abstract
Aim of study. Analysis of literature data on the use of extracorporeal membrane oxygenation in acute chemical poisoning.
Material and methods. The search for domestic publications was carried out in the Elibrary database, foreign publications — in the MEDLINE / PubMed, Google Scholar databases for the period of 2010–2023. The terms used as a search query were according to the official MeSH terms: “Extracorporeal Membrane Oxygenation” OR “Membrane Oxygenation, Extracorporeal” OR “ECMO Treatment” AND “poisoning”.
Results. This review provides information on the outcomes of the use of veno-arterial and veno-venous extracorporeal membrane oxygenation (ECMO) for refractory cardiogenic shock, cardiac arrest and severe ARDS in acute chemical poisoning.
Conclusion. Data analysis showed that in patients with acute chemical poisoning, the incidence of complications and mortality was lower when ECMO/ECMOCPR was included in the complex therapy compared with patients in whom other reasons (not related to acute poisoning) served as indications for the use of this technique. This is probably due to the fact that patients in the group with acute poisoning are younger, they have fewer concomitant diseases; and ECMO is required, as a rule, for a shorter period of time before the toxicant is eliminated from the body using the methods of their elimination and restoration of disturbed functions.
About the Authors
A. Yu. Simonova
N.V. Sklifosovsky Research Institute for Emergency Medicine;
Russian Medical Academy of Continuous Professional Education;
Research and Applied Toxicology Center of the Federal Medical-Biological Agency
Russian Federation
Russian Federation
Anastasia Yu. Simonova - Candidate of Medical Sciences, Leading Researcher, Department of Acute Poisonings and Somatopsychiatric Disorders, 3, B. Sukharevskaya Sq., 129090, Moscow;
Assistant, Department of Clinical Toxicology, bldg. 1, 2/1, Barrikadnaya St., 125993, Moscow;
Senior Researcher, bldg. 7, 3, B. Sukharevskaya Sq., 129090, Moscow
M. M. Potskhveriya
N.V. Sklifosovsky Research Institute for Emergency Medicine;
Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Mikhail M. Potskhveriya - Candidate of Medical Sciences, Head, Department of Acute Poisonings and Somatopsychiatric Disorders, 3, B. Sukharevskaya Sq., 129090, Moscow;
Associate Professor, Department of Clinical Toxicology, bldg. 1, 2/1, Barrikadnaya St., 125993, Moscow
S. V. Zhuravel
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Sergey V. Zhuravel - Doctor of Medical Sciences, Head, Department of Anesthesiology,
3, B. Sukharevskaya Sq., 129090, Moscow
S. S. Petrikov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Sergey S. Petrikov - Corresponding Member of the Russian Academy of Sciences, Professor, Doctor of Medical Sciences, Director,
3, B. Sukharevskaya Sq., 129090, Moscow
A. M. Talyzin
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Alexey M. Talyzin - Head, Department of Anesthesiology No. 3,
3, B. Sukharevskaya Sq., 129090, Moscow
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Simonova A.Yu., Potskhveriya M.M., Zhuravel S.V., Petrikov S.S., Talyzin A.M. The Role of Extracorporeal Membrane Oxygenation in the Complex Treatment of Acute Chemical Poisoning. Russian Sklifosovsky Journal "Emergency Medical Care". 2023;12(3):448-457. https://doi.org/10.23934/2223-9022-2023-12-3-448-457
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