Патогенетические механизмы органной дисфункции при тяжелой сочетанной травме
https://doi.org/10.23934/2223-9022-2023-12-1-92-98
Аннотация
Тяжелая сочетанная травма на протяжении многих лет представляет собой большую демографическую и медицинскую проблему, являясь причиной высокой смертности трудоспособного населения. Одномоментное образование массива разрушенных тканей «запускает» системную воспалительную реакцию, которая на фоне травматического и геморрагического шока приводит к дисбалансу иммунной реактивности и предрасполагает к развитию септических осложнений. В обзоре представлены основные понятия о посттравматических реакциях и нарушениях баланса клеточных и гуморальных иммунных механизмов, приводящих к развитию осложнений.
Об авторе
Г. В. Булава
Лаборатория клинической иммунологии ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ»
Россия
Россия
Булава Галина Владимировна, доктор медицинских наук, научный консультант
129090, Москва, Б. Сухаревская пл., д. 3
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Рецензия
Для цитирования:
Булава Г.В. Патогенетические механизмы органной дисфункции при тяжелой сочетанной травме. Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь». 2023;12(1):92-98. https://doi.org/10.23934/2223-9022-2023-12-1-92-98
For citation:
Bulava G.V. Pathogenetic Mechanisms of Organ Dysfunction in Severe Concomitant Trauma. Russian Sklifosovsky Journal "Emergency Medical Care". 2023;12(1):92-98. https://doi.org/10.23934/2223-9022-2023-12-1-92-98
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