Course and Outcomes of Acute Coronary Syndrome in the Presence of New Coronavirus Infection COVID-19
L. S. Kokov,
S. S. Petrikov,
M. M. Pisankina,
E. A. Dashevsky,
K. A. Popugayev,
M. V. Parkhomenko,
I. M. Kuzmina,
I. S. Babayan,
K. I. Vorontsova,
L. T. Khamidova,
E. V. Klychnikova,
S. P. Goncharov,
A. A. Spassky,
A. I. Kramarenko https://doi.org/10.23934/2223-9022-2022-11-2-238-248
Abstract
Abstract We analyzed the clinical condition of patients with COVID-19 of varying severity, changes in instrumental and laboratory parameters, and assessed the impact of the severity of the course of a new coronavirus infection on the outcomes of acute coronary syndrome.
AIM OF STUDY To study the mutual influence of acute coronary syndrome and the new coronavirus infection COVID-19 on the nature of the course and outcomes of the disease.
Materia l and methods In March 21, 2020 – May 31, 2021, 3 625 patients were treated for COVID-19, including 131 patients with acute coronary syndrome due to COVID-19 disease. All patients underwent a number of studies: computed tomography of the chest, electrocardiography, echocardiography, monitoring of biomarkers of myocardial damage, diagnostic coronary angiography and, if necessary, intracoronary therapeutic intervention.
Results Data on the distribution of patients with COVID-19 according to the presence or absence of ST segment elevation on the electrocardiogram and the degree of lung tissue damage, as well as information on mortality in these groups, are presented. The role of troponin I in the assessment of myocardial ischemia was analyzed. The direct dependence of its level on the volume of lung damage was found. The inverse relationship was shown between the degree of damage to the lung tissue and the indices of oxygen saturation in the blood. A poor prognostic value of low left ventricular ejection fraction in patients with COVID-19 disease has been described.
Conclusions The development of acute coronary syndrome in the course of COVID-19 significantly worsens the prognosis of the disease, which requires the development of algorithms for providing medical care to patients in this category, as well as maximum vigilance in their treatment.
About the Authors
L. S. Kokov
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Leonid S. Kokov - Doctor of Medical Sciences, Professor, Member of the Russian Academy of Sciences, Head of the Department of Emergency Cardiology and Cardiovascular Surgery; Head of the Department of Diagnostic Radiology; Head of the Department of X-ray Endovascular and Vascular Surgery.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
20, bldg. 1 Delegatskaya St., Moscow 127473, Russian Federation
8, bldg. 2, Trubetskaya Str., Moscow, 119991, Russian Federation
S. S. Petrikov
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation
Russian Federation
Sergey S. Petrikov - Doctor of Medical Sciences, Professor of the Russian Academy of Sciences, Corresponding Member of the Russian Academy of Sciences, Director; Head of the Department of Anesthesiology, Resuscitation and Acute Care.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
20, bldg. 1 Delegatskaya St., Moscow 127473, Russian Federation
M. M. Pisankina
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Maria M. Pysankina, X-ray endovascular Diagnosis and Treatment Physician, Jr. Scientific Researcher of the Department of X-ray Surgical Methods of Diagnosis and Treatment
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
E. A. Dashevsky
V.V. Vinogradov City Clinical Hospital
Russian Federation
Russian Federation
Evgeny A. Dashevsky - X-ray Endovascular Diagnosis and Treatment Physician,.
61, Vavilova St., Moscow, 117292, Russian Federation
K. A. Popugayev
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Burnazyan Federal Medical Biophysical Centre
Russian Federation
Russian Federation
Konstantin A. Popugayev - Doctor of medical sciences, Professor, Head; Head of the Department of Anesthesiology-Resuscitation and Intensive Care of the Biomedical University of Innovation and Continuing Education.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
46 bldg. 8, Zhivopisnaya St., Moscow, 123098, Russian Federation
M. V. Parkhomenko
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and Dentistry; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Mstislav V. Parkhomenko - Head of the Department of X-ray Surgical Methods of Diagnosis and Treatment; Assistant of the Department of Diagnostic Radiology; Assistant of the Department of X-ray Endovascular and Vascular Surgery.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
20, bldg. 1 Delegatskaya St., Moscow 127473, Russian Federation
8, bldg. 2, Trubetskaya Str., Moscow, 119991, Russian Federation
I. M. Kuzmina
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Irina M. Kuzmina - Candidate of Medical Sciences, Head of the Department of Emergency Cardiology for Patients with Myocardial Infarction.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
I. S. Babayan
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Irina S. Babayan - Head of the Cardiological Department for Patients with Myocardial Infarction.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
K. I. Vorontsova
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Kristina I. Vorontsova - Cardiologist, Therapeutic Department.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
L. T. Khamidova
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Layla T. Khamidova - Doctor of Medical Sciences, Head of the Department of Diagnostic Radiology.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
E. V. Klychnikova
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Elena V. Klychnikova - Candidate of Medical Sciences, Head of the Scientific Clinical and Biochemical Laboratory of Emergency Research Methods; high level certificate physician Associate Professor, Department of General Pathology, Faculty of Medicine and Biology.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
1, Ostrovityanova St., Moscow, 117997, Russian Federation
S. P. Goncharov
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Stanislav P. Goncharov - Physician for X-ray Endovascular Diagnosis and Treatment.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
A. A. Spassky
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Aleksandr A. Spassky - Physician for X-ray Endovascular Diagnosis and Treatment.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
A. I. Kramarenko
Department of X-ray Surgical Methods of Diagnosis and Treatment N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Anatoly I. Kramarenko - Physician for X-ray Endovascular Diagnosis and Treatment.
B. Sukharevskaya Sq., Moscow, 129090, Russian Federation
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For citations:
Kokov L.S., Petrikov S.S., Pisankina M.M., Dashevsky E.A., Popugayev K.A., Parkhomenko M.V., Kuzmina I.M., Babayan I.S., Vorontsova K.I., Khamidova L.T., Klychnikova E.V., Goncharov S.P., Spassky A.A., Kramarenko A.I. Course and Outcomes of Acute Coronary Syndrome in the Presence of New Coronavirus Infection COVID-19. Russian Sklifosovsky Journal "Emergency Medical Care". 2022;11(2):238-248. https://doi.org/10.23934/2223-9022-2022-11-2-238-248
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