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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23934/2223-9022-2020-9-2-221-230</article-id><article-id custom-type="elpub" pub-id-type="custom">nmp-935</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Выбор анестезиологического пособия при органосохраняющих операциях по поводу врастания плаценты</article-title><trans-title-group xml:lang="en"><trans-title>The Choice of Anesthesia During Organ-Saving Operations Concerning Patients With Placenta Accreta Spectrum Disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6793-2318</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плахотина</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Plakhotina</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Плахотина Елена Николаевна, доктор медицинских наук, заведующая отделением анестезиологии и реанимации</p><p>142700, Видное, ул. Заводская, д. 17</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Head of the Department of Anesthesiology and Intensive Care</p><p>17 Zavodskaya St., Moscow Region, Vidnoye 142700</p></bio><email xlink:type="simple">enp2004@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3804-7691</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousova</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоусова Тамара Николаевна, кандидат медицинских наук, главный врач</p><p>142700, Видное, ул. Заводская, д. 17</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences</p><p>17 Zavodskaya St., Moscow Region, Vidnoye 142700</p></bio><email xlink:type="simple">beltamara1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2460-1623</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куликов Ильяс Александрович, кандидат медицинских наук, заведующий отделением патологии беременности</p><p>142700, Видное, ул. Заводская, д. 17</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Head of the Department of Pregnancy Pathology</p><p>17 Zavodskaya St., Moscow Region, Vidnoye 142700</p></bio><email xlink:type="simple">aesculap@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9864-7205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Латышев</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Latyshev</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Латышев Роман Вячеславович, врач анестезиолог-реаниматолог отделения анестезиологии и реанимации</p><p>142700, Видное, ул. Заводская, д. 17</p></bio><bio xml:lang="en"><p>Anaesthesiologist-resuscitator, the Department of Anesthesiology and Intensive Care</p><p>17 Zavodskaya St., Moscow Region, Vidnoye 142700</p></bio><email xlink:type="simple">roman_red-green@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7051-0212</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлютина</surname><given-names>К. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlyutina</surname><given-names>K. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлютина Карина Михайловна, врач анестезиолог-реаниматолог отделения анестезиологии и реанимации</p><p>142700, Видное, ул. Заводская, д. 17</p></bio><bio xml:lang="en"><p>17Anaesthesiologist-resuscitator, the Department of Anesthesiology and Intensive Care</p><p>Zavodskaya St., Moscow Region, Vidnoye 142700</p></bio><email xlink:type="simple">pavlyutinak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Видновский перинатальный центр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Vidnovsky Perinatal Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>21</day><month>10</month><year>2020</year></pub-date><volume>9</volume><issue>2</issue><fpage>221</fpage><lpage>230</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Плахотина Е.Н., Белоусова Т.Н., Куликов И.А., Латышев Р.В., Павлютина К.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Плахотина Е.Н., Белоусова Т.Н., Куликов И.А., Латышев Р.В., Павлютина К.М.</copyright-holder><copyright-holder xml:lang="en">Plakhotina E.N., Belousova T.N., Kulikov I.A., Latyshev R.V., Pavlyutina K.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/935">https://www.jnmp.ru/jour/article/view/935</self-uri><abstract><p>Резюме Врастание плаценты (placenta accreta, PAS-disorders) - одно из наиболее серьезных осложнений беременности, сопряженное с риском массивного маточного кровотечения, массивной гемотрансфузии и материнской смертности. Общепринятой стратегией лечения пациенток с врастанием плаценты является перипартальная гистерэктомия. В настоящее время отмечается отчетливая тенденция изменения хирургической тактики в пользу органосохраняющих операций, но исследований, посвященных анестезиологическому обеспечению таких операций, нет.</p><p>Цель исследования Обоснование эффективного и безопасного способа анестезиологического пособия при органосохраняющих операциях по поводу врастания плаценты.</p><p>Материал и методы В исследовании приняли участие 80 пациенток с диагнозом врастания плаценты, который был подтвержден интраоперационно. Всем пациенткам выполнены органосохраняющие операции. В зависимости от способа анестезиологического пособия были сформированы три группы: общей анестезии, субарахноидальной анестезии с плановой конверсией в общую после извлечения плода и эпидуральной анестезии с плановым переходом в общую также после извлечения плода. Выполнено сравнение интраоперационной гемодинамики, показателей эффективности тканевой перфузии, эффективности антиноцицептивной защиты на этапах операции. Проведен сравнительный анализ объемов кровопотери и гемотрансфузии, времени активизации пациенток в послеоперационном периоде, оценки выраженности болевого синдрома в 1-е сутки после операции, длительности пребывания в стационаре до выписки и сравнение оценки новорожденных по шкале Апгар на 1-й и 5-й минутах после извлечения.</p><p>Зак лючение В исследовании показано, что оптимальным способом анестезиологического пособия при органосохраняющих операциях по поводу врастания плаценты является эпидуральная анестезия с ее плановой конверсией в общую анестезию с искусственной вентиляцией легких после извлечения плода. Подобный подход к анестезии позволяет поддерживать стабильность гемодинамического профиля и минимизировать вазопрессорную поддержку, сохранить достаточную производительность сердца и перфузию тканей. Антиноцицептивный эффект сочетания эпидуральной и общей анестезии был выше как на интраоперационном этапе, так и в послеоперационном периоде. Преимуществом эпидуральной анестезии с ее переходом в общую явилось снижение объемов интраоперационной кровопотери и гемотрансфузии. В проведенном исследовании не выявлено различий в неонатальных исходах и сроках госпитализации в стационаре в зависимости от способа анестезиологического пособия.</p></abstract><trans-abstract xml:lang="en"><p>Abstract Placenta accreta (PAS-disorders) is one of the most serious complications of pregnancy, associated with the risk of massive uterine bleeding, massive hemotransfusion and maternal mortality. Peripartum hysterectomy is a common treatment strategy for patients with placenta accreta. Currently, there is a clear trend of changing surgical tactics in favor of organ-saving operations, but there are no studies devoted to anesthesiological support of such operations.</p><p>The aim of the study is to substantiate an effective and safe method of anaesthesia in organ-saving operations for placenta accreta spectrum disorders.</p><p>Materia l and methods The study involved 80 patients with a diagnosis of placenta accreta spectrum disorders, confirmed intraoperatively, who underwent organ-saving operations. The patients were randomized depending on the method of anesthesia into 3 groups: general anesthesia, spinal anesthesia with planned conversion to general after fetal extraction and epidural anesthesia with planned conversion to general also after fetal extraction. The comparison of intraoperative hemodynamics, efficiency of tissue perfusion, efficiency of antinociceptive protection at the stages of surgery was performed. A comparative analysis of the volume of blood loss and blood transfusion, time of patients activation in the postoperative period, severity of pain on the first day after surgery, duration of hospital stay before discharge and comparison of the assessment of the newborn according to Apgar score at first and fifth minute after extraction.</p><p>Conclusion The study shows that the optimal method of anesthesia in organ-saving operations for placenta accreta spectrum disorders is epidural anesthesia with its planned conversion to general anesthesia with an artificial lung ventilation after fetal extraction. Such an approach to anesthesia allows to maintain stable hemodynamic profile with minimal vasopressor support, sufficient heart performance, providing effective tissue perfusion and a high level of antinociceptive protection at the intraoperative stage and reduce the volume of intraoperative blood loss and hemotransfusion. In the current study there were no differences in neonatal outcomes and duration of hospitalization depending on the method of anesthesia. The advantage of epidural anesthesia with its conversion to general anesthesia was earlier activation after surgery and lower intensity of postoperative pain syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>врастание плаценты</kwd><kwd>органосохраняющая операция</kwd><kwd>общая анестезия</kwd><kwd>эпидуральная анестезия</kwd><kwd>субарахноидальная анестезия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>placenta accreta spectrum disorders</kwd><kwd>organ-saving operations</kwd><kwd>general anesthesia</kwd><kwd>epidural anesthesia</kwd><kwd>spinal anesthesia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gielchinsky Y, Rojansry N, Fasouliotis SJ, Ezra Y. Placenta accretasummary of 10 years: a survey of 310 casas. 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