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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nmp-296</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS OF LITERATURE</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ  ВОЗМОЖНОСТИ  СНИЖЕНИЯ  ИНТЕНСИВНОСТИ ГИПЕРМЕТАБОЛИЗМА  ПРИ ТЯЖЕЛОЙ  ТЕРМИЧЕСКОЙ  ТРАВМЕ (ОБЗОР ЛИТЕРАТУРЫ)</article-title><trans-title-group xml:lang="en"><trans-title>RECENT ADVANCES OF HYPERMETABOLIC RESPONSE MODULATION IN SEVERE THERMAL TRAUMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильинский</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilynsky</surname><given-names>M. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильинский Максим Евгеньевич - научный сотрудник отделения лечения острых  эндотоксикозов</p></bio><email xlink:type="simple">tribusverbis@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лященко</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyashchenko</surname><given-names>Y. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рык</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryk</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочаров</surname><given-names>Д. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Bocharov</surname><given-names>D. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-Исследовательский институт Скорой Помощи имени Н.В. Склифосовского, Москва<country>Россия</country></aff><aff xml:lang="en">N.V. Sklifosovsky Researh Institute for Emergency Medicine, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>55</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ильинский М.Е., Лященко Ю.Н., Рык А.А., Бочаров Д.Э., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Ильинский М.Е., Лященко Ю.Н., Рык А.А., Бочаров Д.Э.</copyright-holder><copyright-holder xml:lang="en">Ilynsky M.Y., Lyashchenko Y.N., Ryk A.A., Bocharov D.E.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/296">https://www.jnmp.ru/jour/article/view/296</self-uri><abstract><p>В обзоре освещены ключевые аспекты комплексного подхода к модулированию гиперметаболического ответа, позволяющего улучшить результаты лечения пострадавших с тяжелой ожоговой травмой — фармакологические и нефармакологические методы,  раннее энтеральное  питание и дополнительное  назначение  микронутриентов, ранняя  реабилитация  пациентов, индивидуальная оценка потребностей больного в питательных веществах и контроль адекватности проводимой терапии.</p></abstract><trans-abstract xml:lang="en"><p>The review focuses on key aspects  of complex hypermetabolic response modulation which improve treatment outcomes  in patients with severe thermal  trauma: pharmacologic and non-pharmacologic approaches, early enteral feeding and micronutrients, physiatrics, estimation of individual nutritional requirements and monitoring  of the nutritional support  adequacy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гиперметаболический  ответ</kwd><kwd>ожоговая травма</kwd><kwd>искусственное питание</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypermetabolic response</kwd><kwd>burn injury</kwd><kwd>nutritional support</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Peck M.D. Epidemiology of burns throughout the world. Part I: Distribution and risk factors // Burns. – 2011. – Vol. 37, N. 7. – Р. 1087–1100.</mixed-citation><mixed-citation xml:lang="en">Peck M.D. Epidemiology of burns throughout the world. Part I: Distribution  and risk factors. Burns. 2011;37(7):1087–1100.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Brusselaers N., Monstrey S., Vogelaers D., et al. Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortality // Crit. Care. – 2010. – Vol. 14, N. 5. – R188.</mixed-citation><mixed-citation xml:lang="en">Brusselaers N., Monstrey S., Vogelaers D., et  al. Severe  burn  injury  in Europe: a systematic review  of the  incidence, etiology, morbidity, and mortality. Crit Care. 2010;14(5):188.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wolf S. Critical Care in the Severely burned: organ support and management of complications // Total burn care / ed. D.N. Herndon. – 3rd ed. – London: Saunders Elsevier, 2007. – P. 454–476.</mixed-citation><mixed-citation xml:lang="en">Wolf S. Critical  Care in the  Severely  burned: organ  support and  management of complications. In: ed. Herndon D.N. Total burn care. 3rd ed. London: Saunders Elsevier, 2007. 454–476.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнов С.В., Лященко Ю.Н., Спиридонова Т.Г., Рык А.А. Энтеральное и парентеральное питание пострадавших с термической травмой // Парентеральное и энтеральное питание: нац. руководство / под ред. М.Ш. Хубутия, Т.С. Поповой, А.И. Салтанова. – М.: ГЭОТАРМедиа, 2014. – С. 351–370.</mixed-citation><mixed-citation xml:lang="en">Smirnov  S.V., Lyashchenko Yu.N., Spiridonova T.G., Ryk A.A. Enteral and  parenteral nutrition patients with  thermal injury.  In: eds. Khubutiya  M.Sh., Popova  T.S., Saltanov A.I. Parenteral  and enteral  nutrition: national  leadership. Moscow:  GEOTAR-Media Publ.,  2014. 351–370. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Herndon D.N., Tompkins R.G. Support of the metabolic response to burn injury // Lancet. – 2004. – N. 363. – P. 1895–1902.</mixed-citation><mixed-citation xml:lang="en">Herndon D.N., Tompkins R.G. Support of  the  metabolic response to burn  injury.  Lancet. 2004;363:1895–1902.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимова Л.И. Термические ожоги // Искусственное питание в неотложной хирургии и травматологии / под ред. А.С. Ермолова, М.М. Абакумова. – М.: НИИ СП имени Н.В. Склифосовского, 2001. – С. 239–264.</mixed-citation><mixed-citation xml:lang="en">Gerasimova L.I. Thermal burns. In:  ed. Ermolov  A.S., Abakumov  M.M. Artificial nutrition  in emergency surgery and traumatology. Moscow:  NII SP im. N.V. Sklifosovskogo Publ., 2001. 239–264. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sheridan R.L. A great constitutional disturbance // N. Engl. J. Med. – 2001. – Vol. 345, N. 17. – P. 1271–1272.</mixed-citation><mixed-citation xml:lang="en">Sheridan  R.L.  A  great   constitutional  disturbance.  N  Engl  J   Med. 2001;345(17):1271–1272.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Yu Y.M., Tompkins R.G., Ryan C.M., Young V.R. The metabolic basis of the increase in energy expenditure in severely burned patients // JPEN J. Parenter. Enteral. Nutr. – 1999. – Vol. 23, N. 3. – P. 160–168.</mixed-citation><mixed-citation xml:lang="en">Yu Y.M., Tompkins R.G., Ryan  C.M., Young  V.R. The  metabolic basis of  the  increase in  energy  expenditure in  severely burned patients. J Parenter Enteral Nutr. 1999;23(3):160–168.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Demling R., Seigne P. Metabolic management of patients with severe burns // World J. Surg. – 2000. – Vol. 24, N. 6. – P. 673–680.</mixed-citation><mixed-citation xml:lang="en">Demling  R., Seigne  P. Metabolic management of patients with  severe burns. World J Surg. 2000;24(6):673–680.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Newsome T., Mason A., Pruitt B. Weight loss following thermal injury // Ann. Surg. 1973. – Vol. 178, N. 2. – P. 215–217.</mixed-citation><mixed-citation xml:lang="en">Newsome  T., Mason  A., Pruitt B. Weight  loss following  thermal injury. Ann Surg. 1973;178(2):215–217.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Wilmore D.W. Nutrition and metabolism following thermal injury // Clin. Plast. Surg. – 1974. – Vol. 1, N. 4. – P. 603–619.</mixed-citation><mixed-citation xml:lang="en">Wilmore  D.W. Nutrition and  metabolism following  thermal injury.  Clin Plast Surg. 1974;1(4):603–619.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Jeschke M.G., Mlcak R.P., Finnerty C.C., et al. Burn size determines the inflammatory and hypermetabolic response // Crit. Care. – 2007. – Vol. 11, N. 4. – R90.</mixed-citation><mixed-citation xml:lang="en">Jeschke  M.G., Mlcak R.P., Finnerty C.C., et al. Burn size determines the inflammatory and hypermetabolic response. Crit Care. 2007;11(4):90.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Norbury W.B., Herndon D.N. Modulation of the hypermetabolic response after burn injury // Total burn care / ed. D.N. Herndon D.N. – 3rd ed. – New York: Saunders Elsevier, 2007. – P. 420–433.</mixed-citation><mixed-citation xml:lang="en">Norbury   W.B.,  Herndon  D.N.  Modulation  of  the   hypermetabolic response after  burn  injury. In: ed. Herndon D.N. Total burn care. 3rd ed. New York: Saunders Elsevier, 2007. 420–433.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Zawacki B.E., Spitzer K.W., Mason A.D. Jr., et al. Does increased evaporative water loss cause hypermetabolism in burned patients? // Ann. Surg. – 1970. – Vol. 171, N. 2. – P. 236–240.</mixed-citation><mixed-citation xml:lang="en">Zawacki B.E., Spitzer K.W., Mason A.D. Jr., et al. Does increased evaporative  water  loss cause  hypermetabolism in burned patients? Ann Surg. 1970;171(2):236–240.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wilmore D.W., Mason A.D. Jr., Johnson D.W., Pruitt B.A. Effect of ambient temperature on heat production and heat loss in burn patients // J. Appl. Physiol. – 1975. – Vol. 38, N. 4. – P. 593–597.</mixed-citation><mixed-citation xml:lang="en">Wilmore  D.W., Mason A.D. Jr., Johnson D.W., Pruitt B.A. Effect of ambient  temperature on  heat  production and  heat  loss  in burn  patients. J Appl Physiol. 1975;38(4):593–597.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Williams F.N., Jeschke M.G., Chinkes D.L., et al. Modulation of the hypermetabolic response to trauma: temperature, nutrition, and drugs // J. Am. Coll. Surg. – 2009. – Vol. 208, N. 4. – P. 489–502.</mixed-citation><mixed-citation xml:lang="en">Williams  F.N.,  Jeschke  M.G., Chinkes   D.L., et  al.  Modulation of  the hypermetabolic response to trauma: temperature, nutrition, and drugs. J Am Coll Surg. 2009;208(4):489–502.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Munster A.M., Smith-Meek M., Sharkey P. The effect of early surgical intervention on mortality and cost-effectiveness in burn care, 1978–1991 // Burns. – 1994. – Vol. 20, N. 1. – P. 61–64.</mixed-citation><mixed-citation xml:lang="en">Munster A.M., Smith-Meek M., Sharkey  P. The  effect of early  surgical intervention on  mortality and  cost-effectiveness in  burn  care,  1978–1991. Burns. 1994;20(1):61–64.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ramzy P.I., Barret J.P., Herndon D.N. Thermal injury // Crit. Care Clin. – 1999. – Vol. 15, N. 2. – P. 333–352, ix.</mixed-citation><mixed-citation xml:lang="en">Ramzy  P.I.,  Barret  J.P., Herndon D.N. Thermal injury.  Crit Care Clin. 1999;15(2):333–352.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hart D.W., Wolf S.E., Chinkes D.L., et al. Determinants of skeletal muscle catabolism after severe burn // Ann. Surg. – 2000. – Vol. 232, N. 4. – P. 455–465.</mixed-citation><mixed-citation xml:lang="en">Hart D.W., Wolf S.E., Chinkes  D.L., et al. Determinants of skeletal muscle catabolism after  severe  burn.  Ann Surg. 2000;232(4):455–465.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Cucuzzo N.A., Ferrando A., Herndon D.N. The effects of exercise programming vs traditional outpatient therapy in the rehabilitation of severely burned children // J. Burn Care Rehabil. – 2001. – Vol. 22, N. 3. – P. 214–220.</mixed-citation><mixed-citation xml:lang="en">Cucuzzo  N.A., Ferrando A., Herndon D.N. The effects  of exercise programming vs  traditional outpatient therapy in  the  rehabilitation  of severely burned children. J Burn Care Rehabil. 2001;22(3):214–220.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Murphy K.D., Lee J.O., Herndon D.N. Current pharmacotherapy for the treatment of severe burns // Expert Opin. Pharmacother. – 2003. – Vol. 4, N. 3. – P. 369–384.</mixed-citation><mixed-citation xml:lang="en">Murphy  K.D., Lee J.O., Herndon D.N. Current pharmacotherapy for the treatment of severe  burns. Expert Opin Pharmacother.  2003;4(3):369–384.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Herndon D.N., Rodriguez N.A., Diaz E.C., et al. Long-term propranolol use in severely burned pediatric patients: a randomized controlled study // Ann. Surg. – 2012. – Vol. 256, N. 3. – P. 402–411.</mixed-citation><mixed-citation xml:lang="en">Herndon D.N., Rodriguez N.A., Diaz E.C., et al. Long-term propranolol use  in  severely burned pediatric patients:  a  randomized controlled study.  Ann Surg. 2012;256(3):402–411.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Herndon D.N., Hart D.W., Wolf S.E., et al. Reversal of catabolism by beta-blockade after severe burns // N. Engl. J. Med. – 2001. – Vol. 345, N. 17. – P. 1223–1229.</mixed-citation><mixed-citation xml:lang="en">Herndon D.N., Hart  D.W., Wolf S.E., et  al. Reversal  of catabolism by beta-blockade after  severe  burns. N  Engl J  Med.  2001;345(17):1223–1229.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ali A., Herndon D.N., Mamachen A., et al. Propranolol attenuates hemorrhage and accelerates wound healing in severely burned adults // Crit. Care. – 2015. – N. 19. – P. 217.</mixed-citation><mixed-citation xml:lang="en">Ali A., Herndon D.N., Mamachen A., et al. Propranolol attenuates hemorrhage and  accelerates wound  healing in severely burned adults. Crit Care. 2015;19:217.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hart D.W., Wolf S.E., Ramzy P.I., et al. Anabolic effects of oxandrolone after severe burn // Ann. Surg. – 2001. – Vol. 233, N. 4. – P. 556–564.</mixed-citation><mixed-citation xml:lang="en">Hart  D.W., Wolf S.E., Ramzy P.I., et al. Anabolic  effects  of oxandrolone after  severe  burn.  Ann Surg. 2001;233(4):556–564.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Suman O.E., Thomas S.J., Wilkins J.P., et al. Effect of exogenous growth hormone and exercise on lean mass and muscle function in children with burns // J. Appl. Physiol. – 2003. – Vol. 94, N. 6. – P. 2273–2281.</mixed-citation><mixed-citation xml:lang="en">Suman  O.E., Thomas S.J., Wilkins J.P., et al. Effect of exogenous growth hormone and  exercise on  lean  mass  and  muscle  function in  children with burns. J Appl Physiol. 2003;94(6):2273–2281.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Branski L.K., Herndon D.N., Barrow R.E., et al. Randomized controlled trial to determine the efficacy of long-term growth hormone treatment in severely burned children // Ann. Surg. – 2009. – Vol. 250, N. 4. – P. 514–523.</mixed-citation><mixed-citation xml:lang="en">Branski  L.K., Herndon D.N., Barrow R.E., et al. Randomized controlled trial to determine the efficacy of long-term growth  hormone treatment in severely burned children. Ann Surg. 2009;250(4):514–523.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Takala J., Ruokonen E., Webster N.R., et al. Increased mortality associated with growth hormone treatment in critically ill adults // N. Engl. J. Med. – 1999. – Vol. 341, N. 11. – P. 785–792.</mixed-citation><mixed-citation xml:lang="en">Takala  J., Ruokonen E., Webster N.R., et al. Increased mortality associated  with  growth  hormone treatment in  critically ill adults. N Engl J Med. 1999;341(11):785–792.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Moller S., Jensen M., Svensson P., Skakkebaek N.E. Insulin-like growth factor 1 (IGF-1) in burn patients // Burns. – 1991. – Vol. 17, N. 4. – P. 279–281.</mixed-citation><mixed-citation xml:lang="en">Moller S., Jensen  M., Svensson P., Skakkebaek N.E. Insulin-like growth factor  1 (IGF-1) in burn  patients. Burns. 1991;17(4):279–281.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Langouche L., Van den Berghe G. Glucose metabolism and insulin therapy // Crit. Care Clin. – 2006. – Vol. 22, N. 1. – P. 119–129.</mixed-citation><mixed-citation xml:lang="en">Langouche L., Van  den  Berghe   G. Glucose   metabolism and  insulin therapy. Crit Care Clin. 2006;22(1):119–129.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Gauglitz G.G., Herndon D.N., Kulp G.A., et al. Abnormal insulin sensitivity persists up to three years in pediatric patients post-burn // J. Clin. Endocrinol. Metab. – 2009. – Vol. 94, N. 5. – P. 1656–1664.</mixed-citation><mixed-citation xml:lang="en">Gauglitz G.G., Herndon D.N., Kulp G.A., et al. Abnormal insulin sensitivity  persists up to three years  in pediatric patients post-burn. J Clin Endocrinol Metab. 2009;94(5):1656–1664.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Gornik I., Vujaklija-Brajkovic A., Renar I.P., et al. A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes // Crit. Care. – 2010. – Vol. 14, N. 4. – R130.</mixed-citation><mixed-citation xml:lang="en">Gornik  I., Vujaklija-Brajkovic A., Renar  I.P., et al. A prospective observational study  of the  relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes. Crit Care. 2010;14(4):130.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Pidcoke H.F., Wade C.E., Wolf S.E. Insulin and the burned patient // Crit. Care Med. – 2007. – Vol. 35, N. 9. – Suppl. – S524–S530.</mixed-citation><mixed-citation xml:lang="en">Pidcoke  H.F., Wade C.E., Wolf S.E. Insulin and  the  burned patient. Crit Care Med. 2007;35(9  Suppl):S524–S530.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Jeschke M.G., Klein D., Herndon D.N. Insulin treatment improves the systemic inflammatory reaction to severe trauma // Ann. Surg. – 2004. – Vol. 239, N. 4. – P. 553–560.</mixed-citation><mixed-citation xml:lang="en">Jeschke   M.G.,  Klein  D.,  Herndon  D.N.  Insulin  treatment  improves the   systemic  inflammatory  reaction  to   severe   trauma.  Ann   Surg. 2004;239(4):553–560.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Ferrando A.A., Chinkes D.L., Wolf S.E., et al. A submaximal dose of insulin promotes net skeletal muscle protein synthesis in patients with severe burns // Ann. Surg. – 1999. – Vol. 229. – P. 11–18.</mixed-citation><mixed-citation xml:lang="en">Ferrando A.A., Chinkes  D.L., Wolf  S.E., et  al. A submaximal dose  of insulin promotes net  skeletal muscle  protein synthesis in patients with severe  burns. Ann Surg. 1999;229:11–18.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Dellinger R.P., Levy M.M., Rhodes A., et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012 // Crit. Care Med. – 2013. – Vol. 41., N. 2. – P. 580–637.</mixed-citation><mixed-citation xml:lang="en">Dellinger R.P., Levy M.M., Rhodes  A., et al. Surviving  sepsis  campaign: international  guidelines for  management of severe  sepsis  and  septic shock:  2012. Crit Care Med. 2013;41(2):580–637.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Gore D.C., Wolf S.E., Herndon D.N., et al. Metformin blunts stressinduced hyperglycemia after thermal injury // J. Trauma. – 2003. Vol. 54, N. 3. – P. 555–561.</mixed-citation><mixed-citation xml:lang="en">Gore  D.C., Wolf  S.E., Herndon D.N.,  et  al.  Metformin blunts stressinduced hyperglycemia after  thermal injury. J Trauma. 2003;54(3):555–561.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Gore D.C., Herndon D.N., Wolfe R.R. Comparison of peripheral metabolic effects of insulin and metformin following severe burn injury // J. Trauma. – 2005. – Vol. 59, N. 2. – P. 316–322.</mixed-citation><mixed-citation xml:lang="en">Gore D.C., Herndon D.N., Wolfe R.R. Comparison of peripheral metabolic  effects  of insulin and  metformin following  severe  burn  injury.  J Trauma. 2005;59(2):316–322.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Luft D., Schmulling R.M., Eggstein M. Lactic acidosis in biguanide treated diabetics: a review of 330 cases // Diabetologia. – 1978. – Vol. 14, N. 2. – P. 75–87.</mixed-citation><mixed-citation xml:lang="en">Luft D., Schmulling R.M., Eggstein M. Lactic acidosis in biguanidetreated diabetics: a review of 330 cases. Diabetologia. 1978;14(2):75–87.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Bailey C.J., Turner R.C. Metformin // N. Engl. J. Med. – 1996. – Vol. 334, N. 9. – P. 574–579.</mixed-citation><mixed-citation xml:lang="en">Bailey C.J., Turner R.C. Metformin. N Engl J Med. 1996;334(9):574–579.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Williams F.N., Branski L.K., Jeschke M.G., et al. What, How, and How Much Should Patients with Burns be Fed? // Surg. Clin. North Am. – 2011. – Vol. 91, N. 3. – P. 609–629.</mixed-citation><mixed-citation xml:lang="en">Williams   F.N.,  Branski   L.K.,  Jeschke   M.G.,  et   al.  What,   How,  and How Much  Should  Patients with  Burns  be  Fed?  Surg Clin North  Am. 2011;91(3):609–629.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">СмирновС.В., Лященко Ю.Н., Рык А.А., Хватов В.Б. Современные подходы к питательной поддержке в интенсивной терапии пациентов с термической травмой в стационаре скорой помощи // Скорая медицинская помощь. – 2010. – № 1. – С. 25–38.</mixed-citation><mixed-citation xml:lang="en">Smirnov   S.V.,  Lyashchenko  Yu.N.,  Ryk  A.A.,  Khvatov   V.B.  Modern approaches  to  nutritional  support in  intensive  care   patients  with thermal injuries in a hospital emergency room.  Skoraya meditsinskaya pomoshch’. 2010;1:25–38. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Rousseau A.F., Losser M.R., Ichai C., Berger M.M. ESPEN endorsed recommendations: nutritional therapy in major burns // Clin. Nutr. – 2013. – Vol. 32, N. 4. – P. 497–502.</mixed-citation><mixed-citation xml:lang="en">Rousseau A.F., Losser  M.R., Ichai  C., Berger  M.M. ESPEN endorsed recommendations:  nutritional  therapy  in  major   burns.  Clin  Nutr. 2013;32(4):497–502.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Deitch E.A. Intestinal permeability is increased in burn patients shortly after injury // Surgery. – 1990. – Vol. 107, N. 4. – P. 411–416.</mixed-citation><mixed-citation xml:lang="en">Deitch  E.A. Intestinal permeability is increased in burn patients shortly after  injury.  Surgery. 1990;107(4):411–416.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Mochizuki H., Trocki O., Dominioni L., et al. Mechanism of prevention of postburn hypermetabolism an catabolism by early enteral feeding // Ann. Surg. – 1984. – Vol. 200, N. 3. – P. 297–310.</mixed-citation><mixed-citation xml:lang="en">Mochizuki H., Trocki O., Dominioni L., et al. Mechanism of prevention of postburn hypermetabolism an  catabolism by early  enteral feeding. Ann Surg. 1984;200(3):297–310.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Chiarelli A., Enzi G., Casadei A., et al. Very early nutrition supplementation in burned patients // Am. J. Clin. Nutr. – 1990. – Vol. 51, N. 6. – P. 1035–1039.</mixed-citation><mixed-citation xml:lang="en">Chiarelli A., Enzi G., Casadei A., et al. Very early nutrition supplementation  in burned patients. Am J Clin Nutr. 1990;51(6):1035–1039.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">McDonald W.S., Sharp C.W. Jr. Deitch E.A. Immediate enteral feeding in burn patients is safe and effective // Ann. Surg. – 1991. – Vol. 213, N. 2. – P. 177–183.</mixed-citation><mixed-citation xml:lang="en">McDonald W.S., Sharp C.W. Jr. Deitch  E.A. Immediate enteral feeding  in burn  patients is safe and effective. Ann Surg. 1991;213(2):177–183.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Venter M., Rode H., Sive A., Visser M. Enteral resuscitation and early enteral feeding in children with major burns-effect on McFarlane response to stress // Burns. – 2007. – Vol. 33, N. 4. – P. 464–471.</mixed-citation><mixed-citation xml:lang="en">Venter  M., Rode H., Sive A., Visser  M. Enteral resuscitation and  early enteral feeding   in  children with  major   burns–Effect  on  McFarlane response to stress. Burns. 2007;33(4):464–471.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Barton R., Craft W., Mone M.C., Saffle J. Chemical paralysis reduces energy expenditure in mechanically ventilated trauma patients // J. Burn Care Rehabil. – 1997. – Vol. 18, N. 5. – P. 461–468.</mixed-citation><mixed-citation xml:lang="en">Barton  R., Craft W., Mone  M.C., Saffle  J. Chemical paralysis reduces energy  expenditure in mechanically ventilated trauma patients. J Burn Care Rehabil. 1997;18(5):461–468.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Saffle J., Medina E., Raymond J., et al. Use of indirect calorimetry in the nutritional management of burn patients // J. Trauma. – 1985. – Vol. 25, N. 1. – P. 32–39.</mixed-citation><mixed-citation xml:lang="en">Saffle J., Medina E., Raymond J., et al. Use of indirect calorimetry in the nutritional management of burn  patients. J Trauma. 1985;25(1):32–39.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Swinamer D., Phang P., Jones R., et al. Twenty-four hour energy expenditure in critically ill patient // Crit. Care Med. – 1987. – Vol. 15, N. 7. – P. 637–641.</mixed-citation><mixed-citation xml:lang="en">Swinamer D., Phang  P., Jones R., et al. Twenty-four hour energy expenditure  in critically ill patient. Crit Care Med. 1987;15(7):637–641.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Shaw-Delanty S., Elwyn D., Askanazi J., et al. Resting energy expenditure in injured, septic, and malnourished adult patients on intravenous diets // Clin. Nutr. – 1990. – Vol. 9, N. 6. – P. 305–312.</mixed-citation><mixed-citation xml:lang="en">Shaw-Delanty S., Elwyn D., Askanazi  J., et al. Resting energy  expenditure  in injured, septic, and malnourished adult  patients on intravenous diets.  Clin Nutr. 1990;9(6):305–312.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Hester D., Lawson K. Suggested guidelines for use by dietitians in the interpretation of indirect calorimetry data // J. Amer. Diet. Assoc. – 1989. – Vol. 89, N. 1. – P. 100–101.</mixed-citation><mixed-citation xml:lang="en">Hester D.,  Lawson  K. Suggested guidelines  for  use  by  dietitians in the   interpretation of  indirect  calorimetry data.   J  Amer  Diet  Assoc. 1989;89(1):100–101.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Rimdeika R., Gudaviciene D., Adamonis K., et al. The effectiveness of caloric value of enteral nutrition in patients with major burns // Burns. – 2006. – Vol. 32, N. 1. – P. 83–86.</mixed-citation><mixed-citation xml:lang="en">Rimdeika  R., Gudaviciene D., Adamonis K., et  al. The  effectiveness of caloric  value  of enteral nutrition in patients with  major  burns. Burns. 2006;32(1):83–86.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Berger M.M., Revelly J.P., Wasserfallen J.B., et al. Impact of a computerized information system on quality of nutritional support in the ICU // Nutrition. – 2006. – Vol. 22, N. 3. – P. 221–229.</mixed-citation><mixed-citation xml:lang="en">Berger M.M., Revelly J.P., Wasserfallen J.B., et al. Impact of a computerized  information system on quality of nutritional support in the  ICU. Nutrition.  2006;22(3):221–229.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Masters B., Aarabi S., Sidhwa F., Wood F. High-carbohydrate, high-protein, low-fat versus low-carbohydrate, high-protein, high-fat enteral feeds for burns // Cochrane Database Syst Rev. – 2012. – Vol. 1. – CD006122.</mixed-citation><mixed-citation xml:lang="en">Masters B., Aarabi S., Sidhwa F., Wood F. High-carbohydrate, high-protein,  low-fat versus  low-carbohydrate, high-protein, high-fat enteral feeds for burns. Cochrane Database Syst Rev. 2012;1:CD006122.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson B.R., Galiatsatos P., Rabiee A., et al. Intensive insulin therapy confers a similar survival benefit in the burn intensive care unit to the surgical intensive care unit // Surgery. – 2009. – Vol. 146, N. 5. – P. 922–930.</mixed-citation><mixed-citation xml:lang="en">Gibson  B.R., Galiatsatos P., Rabiee  A., et  al. Intensive insulin therapy confers a similar survival  benefit in the  burn  intensive care unit  to the surgical intensive care unit. Surgery. 2009;146(5):922–930.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Pham T.N., Warren A.J., Phan H.H., et al. Impact of tight glycemic control in severely burned children // J. Trauma. – 2005. – Vol. 59, N. 5. – P. 1148–1154.</mixed-citation><mixed-citation xml:lang="en">Pham  T.N., Warren  A.J., Phan  H.H., et al. Impact of tight glycemic  control in severely burned children. J Trauma. 2005;59(5):1148–1154.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Pidcoke H.F., Wanek S.M., Rohleder L.S., et al. Glucose variability is associated with high mortality after severe burn // J. Trauma. – 2009. – Vol. 67, N. 5. – P. 990–995.</mixed-citation><mixed-citation xml:lang="en">Pidcoke   H.F.,  Wanek   S.M.,  Rohleder  L.S.,  et   al.  Glucose   variability  is  associated  with   high   mortality  after   severe   burn.   J   Trauma. 2009;67(5):990–995.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Jeschke M.G., Kulp G.A., Kraft R., et al. Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial // Am. J. Respir. Crit. Care Med. – 2010. –– Vol. 182, N. 3. – P. 351–359.</mixed-citation><mixed-citation xml:lang="en">Jeschke  M.G., Kulp  G.A., Kraft R., et  al. Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial.  Am J Respir Crit Care Med. 2010;182(3):351–359.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">van Zanten A.R., Dhaliwal R., Garrel D., et al. Enteral glutamine supplementation in critically ill patients: a systematic review and metaanalysis // Crit. Care. – 2015. – Vol. 19. – P. 294.</mixed-citation><mixed-citation xml:lang="en">van  Zanten A.R., Dhaliwal  R., Garrel  D., et  al. Enteral glutamine supplementation in critically ill patients: a systematic review  and  metaanalysis. Crit Care. 2015;19:294.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Coudray-Lucas C., LeBever H., Cynober L., et al. Ornithine aketoglutarate improves wound healing in severe burn patients: a prospective randomized double-blind trial versus isonitrogenous controls // Crit. Care Med. – 2000. – Vol. 28, N. 6. – P. 1772–1776.</mixed-citation><mixed-citation xml:lang="en">Coudray-Lucas C., LeBever  H., Cynober  L., et  al. Ornithine aketoglutarate improves wound  healing in severe  burn  patients: a prospective randomized double-blind trial versus  isonitrogenous controls. Crit Care Med. 2000;28(6):1772–1776.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Yan H., Peng X., Huang Y., et al. Effects of early enteral arginine supplementation on resuscitation of severe burn patients // Burns. – 2007. – Vol. 33, N. 2. – P. 179–184.</mixed-citation><mixed-citation xml:lang="en">Yan  H.,  Peng  X., Huang   Y., et  al.  Effects  of  early  enteral  arginine supplementation  on   resuscitation  of  severe   burn   patients.  Burns. 2007;33(2):179–184.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Gamliel Z., DeBiasse M., Demling R. Essential microminerals and their response to burn injury // J. Burn Care Rehabil. – 1996. – Vol. 17, N. 3. – P. 264–272.</mixed-citation><mixed-citation xml:lang="en">Gamliel  Z., DeBiasse  M., Demling  R. Essential microminerals and their response to burn  injury.  J Burn Care Rehabil. 1996;17(3):264–272.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Gottschlich M., Warden G. Vitamin supplementation in the patient with burns // J. Burn Care Rehabil. – 1990. – Vol. 11, N. 3. – P. 275–279.</mixed-citation><mixed-citation xml:lang="en">Gottschlich M., Warden G. Vitamin supplementation in the patient with burns. J Burn Care Rehabil. 1990;11(3):275–279.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Mayes T., Gottschlich M., Warden G. Clinical nutrition protocols for continuous quality improvement in the outcomes of patients with burns // J. Burn Care Rehabil. – 1997. –Vol. 18, N. 4. – P. 365–368.</mixed-citation><mixed-citation xml:lang="en">Mayes  T., Gottschlich M., Warden G. Clinical  nutrition protocols for continuous  quality improvement  in  the   outcomes of  patients  with burns. J Burn Care Rehabil. 1997;18(4):365–368.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Barbosa E., Faintuch J., Machado Moreira E.A., et al. Supplementation of vitamin E, vitamin C, and zinc attenuates oxidative stress in burned children: a randomized, double-blind, placebo-controlled pilot study // J. Burn Care Res. – 2009. – Vol. 30, N. 5. – P. 859–866.</mixed-citation><mixed-citation xml:lang="en">Barbosa  E., Faintuch J., Machado  Moreira  E.A., et al. Supplementation of vitamin E, vitamin C, and zinc attenuates oxidative stress in burned children: a randomized, double-blind, placebo-controlled pilot study.  J Burn Care Res. 2009;30(5):859–866.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Tanaka H., Matsuda T., Miyagantani Y., et al. Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration // Arch. Surg. – 2000. –Vol. 135, N. 3. – P. 326–331.</mixed-citation><mixed-citation xml:lang="en">Tanaka  H., Matsuda T., Miyagantani Y., et al. Reduction of resuscitation fluid volumes in severely burned patients using  ascorbic acid administration. Arch. Surg. 2000;135(3):326–331.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Falder S., Silla R., Phillips M., et al. Thiamine supplementation increases serum thiamine and reduces pyruvate and lactate levels in burn patients // Burns. – 2010. – Vol. 36, N. 2. – P. 261–269.</mixed-citation><mixed-citation xml:lang="en">Falder S., Silla R., Phillips M., et al. Thiamine supplementation increases  serum   thiamine and  reduces pyruvate and  lactate levels  in  burn patients. Burns. 2010;36(2):261–269.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Klein G.L., Herndon D.N., Chen T.C., et al. Standard multivitamin supplementation does not improve vitamin D insufficiency after burns // J. Bone Miner. Metab. – 2009. – Vol. 27, N. 4. – P. 502–506.</mixed-citation><mixed-citation xml:lang="en">Klein G.L., Herndon D.N., Chen  T.C., et al. Standard multivitamin supplementation does  not improve vitamin D insufficiency after  burns. J Bone Miner Metab. 2009;27(4):502–506.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Berger M.M., Baines M., Raffoul W., et al. Trace element supplements after major burns modulate antioxidant status andclinical course by way of increased tissue trace element concentration // Am. J. Clin. Nutr. – 2007. – Vol. 85, N. 5. – P. 1293–300.</mixed-citation><mixed-citation xml:lang="en">Berger  M.M., Baines  M., Raffoul  W., et al. Trace  element supplements after  major  burns  modulate antioxidant status andclinical course by way of increased tissue trace  element concentration. Am  J  Clin Nutr. 2007;85(5):1293–300.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Magnotti L., Deitch E. Burns, bacterial translocation, gut barrier function, and failure // J. Burn Care Rehabil. – 2005. – Vol. 26, N. 5. – P. 383–391.</mixed-citation><mixed-citation xml:lang="en">Magnotti L., Deitch  E. Burns,  bacterial translocation, gut  barrier function,  and failure. J Burn Care Rehabil. 2005;26(5):383–391.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Fong Y., Marano M., Barber E., et al. Total parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans // Ann. Surg. – 1989. – Vol. 210, N. 4. – P. 449–454.</mixed-citation><mixed-citation xml:lang="en">Fong  Y., Marano  M., Barber  E., et  al.  Total  parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans. Ann Surg. 1989;210(4):449–454.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Barret J.P., Jeschke M.G., Herndon D.N. Fatty infiltration of the liver in severely burned pediatric patients: autopsy findings and clinical implications // J. Trauma. – 2001. – Vol. 51, N. 4. – P. 736–739.</mixed-citation><mixed-citation xml:lang="en">Barret  J.P., Jeschke  M.G., Herndon D.N. Fatty infiltration of the  liver in severely burned pediatric patients: autopsy findings and clinical  implications. J Trauma. 2001;51(4):736–739.</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Andel H., Rab M., Andel D., et al. Impact of duodenal feeding on the oxygen balance of the splanchnic region during different phases of severe burn injury // Burns. – 2002. – Vol. 28, N. 1. – P. 60–64.</mixed-citation><mixed-citation xml:lang="en">Andel  H., Rab M., Andel  D., et  al. Impact of duodenal feeding  on  the oxygen  balance of  the  splanchnic region during different phases of severe  burn  injury.  Burns. 2002;28(1):60–64.</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Saito H., Trocki O., Alexander J., et al. The effect of route of nutrient administration on the nutritional state, catabolic hormone secretion and gut mucosal integrity after burn injury // JPEN. – 1987. – Vol. 11, N. 1. – P. 1–7.</mixed-citation><mixed-citation xml:lang="en">Saito  H., Trocki  O., Alexander J., et  al. The  effect of route of nutrient administration on  the  nutritional state, catabolic hormone secretion and gut mucosal integrity after  burn  injury.  JPEN. 1987;11(1):1–7.</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Stroud M., Duncan H., Nightingale J., et al. Guidelines for enteral feeding in adult hospital patients // Gut. – 2003. – Vol. 52. – Suppl 7. – vii1– vii12.</mixed-citation><mixed-citation xml:lang="en">Stroud  M., Duncan H., Nightingale J., et al. Guidelines for enteral feeding in adult  hospital patients. Gut. 2003;52(Suppl 7):vii1-vii12.</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Kowal-Vern A., McGill V., Gamelli R. Ischemic necrotic bowel disease in thermal injury // Arch Surg. – 1997. –– Vol. 132, N. 4. – P. 440–443.</mixed-citation><mixed-citation xml:lang="en">Kowal-Vern A., McGill V., Gamelli R. Ischemic necrotic bowel disease in thermal injury.  Arch Surg. 1997;132(4):440–443.</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Markell K.W., Renz E.M., White C.E., et al. Abdominal complications after severe burns // J. Am. Coll. Surg. – 2009. –Vol. 208, N. 5. – P. 940–947.</mixed-citation><mixed-citation xml:lang="en">Markell  K.W., Renz  E.M., White  C.E., et  al. Abdominal complications after  severe  burns. J Am Coll Surg. 2009;208(5):940–947.</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Eisenberg P. Causes of diarrhea in tube-fed patients: a comprehensive approach to diagnosis and management // Nutr. Clin. Pract. – 1993. – Vol. 8, N. 3. – P. 119–123.</mixed-citation><mixed-citation xml:lang="en">Eisenberg P. Causes  of diarrhea in tube-fed patients: a comprehensive approach to diagnosis and management. Nutr Clin Pract. 1993;8(3):119–123.</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Kealey G., Aguillar J., Lewis R., et al. Cadaver skin allografts and transmission of human cytomegalovirus to burn patients // J. Am. Coll. Surg. – 1996. – Vol. 182, N. 3. – P. 201–205.</mixed-citation><mixed-citation xml:lang="en">Kealey G., Aguillar  J., Lewis R., et al. Cadaver  skin allografts and transmission of human cytomegalovirus to  burn  patients. J  Am  Coll Surg. 1996;182(3):201–205.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Grube B.J., Heimbach D.M., Marvin J.A. Clostridium difficile diarrhea in critically ill burned patients // Arch. Surg. – 1987. – Vol. 122, N. 6. – P. 655–661.</mixed-citation><mixed-citation xml:lang="en">Grube B.J., Heimbach D.M., Marvin J.A. Clostridium difficile diarrhea in critically ill burned patients. Arch Surg. 1987;122(6):655–661.</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Gottschlich M., Warden G., Michel M., et al. Diarrhea in tube-fed burn patients: incidence, etiology, nutritional impact, and prevention // JPEN. – 1988. – Vol. 12, N. 4. – P. 338–345.</mixed-citation><mixed-citation xml:lang="en">Gottschlich M., Warden G., Michel M., et al. Diarrhea in tube-fed burn patients: incidence, etiology, nutritional impact, and prevention. JPEN. 1988;12(4):338–345.</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Whelan K., Schneider S.M. Mechanisms, prevention, and management of diarrhea in enteral nutrition // Curr Opin. Gastroenterol. – 2011. – Vol. 27, N. 2. – P. 152–159.</mixed-citation><mixed-citation xml:lang="en">Whelan K., Schneider S.M. Mechanisms, prevention, and management of diarrhea in enteral nutrition. Curr Opin Gastroenterol.  2011;27(2):152–159.</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Scaife C.L., Saffle J.R., Morris S.E. Intestinal obstruction secondary to enteral feedings in burn trauma patients // J. Trauma. – 1999. – Vol. 47, N. 5. – P. 859–863.</mixed-citation><mixed-citation xml:lang="en">Scaife C.L., Saffle J.R., Morris  S.E. Intestinal obstruction secondary to enteral feedings in  burn  trauma patients. J  Trauma.  1999;47(5):859–863.</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Gump F., Kinney J. Energy balance and weight loss in burned patients // Arch. Surg. – 1971. – Vol. 103, N. 4. –P. 442–448.</mixed-citation><mixed-citation xml:lang="en">Gump F., Kinney  J. Energy  balance and  weight  loss in burned patients. Arch Surg. 1971;103(4):442–448.</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Zdolsek H.J., Lindahl O.A., Angquist K.A., Sjöberg F. Non-invasive assessment of intercompartmental fluid shifts in burn victims // Burns. – 1998. – Vol. 24, N. 3. – P. 233–240.</mixed-citation><mixed-citation xml:lang="en">Zdolsek   H.J.,  Lindahl   O.A.,  Angquist  K.A., Sjöberg   F.  Non-invasive assessment of intercompartmental fluid  shifts  in burn  victims. Burns. 1998;24(3):233–240.</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Streat S., Beddoe A., Hill G. Aggressive nutritional support does not prevent protein loss despite fat gain in septic intensive care patients // J. Trauma. – 1987. – Vol. 27, N. 3. – P. 262–266.</mixed-citation><mixed-citation xml:lang="en">Streat S., Beddoe  A., Hill G. Aggressive  nutritional support does  not prevent protein loss despite fat gain in septic  intensive care patients. J Trauma. 1987;27(3):262–266.</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Hart D.W., Wolf S.E., Herndon D.N., et al. Energy expenditure and caloric balance after burn: Increased feeding leads to fat rather than lean mass accretion // Ann. Surg. – 2002. – Vol. 235, N. 1. – P. 152–161.</mixed-citation><mixed-citation xml:lang="en">Hart  D.W.,  Wolf  S.E.,  Herndon D.N.,  et  al.  Energy  expenditure and caloric  balance after  burn:  Increased feeding  leads  to  fat  rather than lean mass accretion. Ann Surg. 2002;235(1):152–161.</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Graves C., Saffle J., Morris S. Comparison of urine urea nitrogen collection times in critically ill patients // Nutr. Clin. Pract. – 2005. – Vol. 20. – N. 2. – P. 271–275.</mixed-citation><mixed-citation xml:lang="en">Graves  C., Saffle  J., Morris  S. Comparison of urine  urea  nitrogen collection times in critically ill patients. Nutr Clin Pract. 2005;20(2):271–275.</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Konstantinides F., Radmer W., Becker W., et al. Inaccuracy of nitrogen balance determinations in thermal injury with calculated total urinary nitrogen // J. Burn Care Rehabil. – 1992. – Vol. 13, N. 2. – Pt. 1. – P. 254–260.</mixed-citation><mixed-citation xml:lang="en">Konstantinides F., Radmer  W., Becker W., et al. Inaccuracy of nitrogen balance determinations in thermal injury  with calculated total urinary nitrogen. J Burn Care Rehabil. 1992;13(2)Pt1:254–260.</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">LeBlanc A., Gogia P., Schneider V., et al. Calf muscle area and strength changes after five weeks of horizontal bed rest // Am. J. Sports Med. – 1988. – Vol. 16, N. 6. – P. 624–629.</mixed-citation><mixed-citation xml:lang="en">LeBlanc A., Gogia P., Schneider V., et al. Calf muscle  area  and strength changes after   five  weeks  of  horizontal bed  rest.   Am  J  Sports  Med. 1988;16(6):624–629.</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Greenhalgh D.G., Housinger T.A., Kagan R.J., et al. Maintenance of serum albumin levels in pediatric burn patients: a prospective, randomized trial // J. Trauma. – 1995. – Vol. 39, N. 1. – P. 67–73.</mixed-citation><mixed-citation xml:lang="en">Greenhalgh D.G., Housinger T.A.,  Kagan  R.J., et  al.  Maintenance  of serum  albumin levels  in pediatric burn  patients: a prospective, randomized trial.  J Trauma. 1995;39(1):67–73.</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Sheridan R.L., Prelack K., Cunningham J.J. Physiologic hypoalbuminemia is well tolerated by severely burned children // J. Trauma. – 1997. – Vol. 43, N. 3. – P. 448–452.</mixed-citation><mixed-citation xml:lang="en">Sheridan  R.L.,  Prelack   K.,  Cunningham  J.J.  Physiologic  hypoalbuminemia  is  well  tolerated  by  severely burned  children.  J   Trauma. 1997;43(3):448–452.</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">Rettmer R., Williamson J., Labbe R., et al. Laboratory monitoring of nutrition status in burn patients // Clin. Chem. – 1992. – Vol. 38, N. 3. – P. 334–337.</mixed-citation><mixed-citation xml:lang="en">Rettmer R., Williamson J., Labbe  R., et  al. Laboratory monitoring  of nutrition status in burn  patients. Clin Chem. 1992;38(3):334–337.</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">Cynober L., Prugnaud O., Lioret H., et al. Serum transtyretin levels in patients with burn injury // Surgery. – 1991. – Vol. 109, N. 5. – P. 640–644.</mixed-citation><mixed-citation xml:lang="en">Cynober  L., Prugnaud O., Lioret  H., et al. Serum  transtyretin levels  in patients with burn  injury.  Surgery. 1991;109(5):640–644.</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">Manelli J., Abdetii C., Botti G., et al. A reference standard for plasma proteins is required for nutritional assessment of adult burn patients // Burns. – 1998. – Vol. 24, N. 4. – P. 337–345.</mixed-citation><mixed-citation xml:lang="en">Manelli  J., Abdetii  C., Botti G., et  al. A reference standard for plasma proteins is required for nutritional assessment of adult  burn  patients. Burns. 1998;24(4):337–345.</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Saffrey J.R., Graves C., Cochran A. Nutritional support of the burned patient // Total burn care / ed. D.N. Herndon. – 4th ed. – New York: Saunders Elsevier, 2012. – P. 348–349.</mixed-citation><mixed-citation xml:lang="en">Saffrey  J.R., Graves  C., Cochran A. Nutritional support of the  burned patient. In: ed. Herndon D.N. Total burn care. 4th  ed. New York: Saunders Elsevier, 2012. 348–349.</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Kyle U.G., Nicod L., Raguso C., et al. Fat-free mass change to weight change ratio during refeeding following lung transplantation // Acta Diabetol. – 2003. – Vol. 40, Suppl. 1. – S165–S167.</mixed-citation><mixed-citation xml:lang="en">Kyle U.G., Nicod  L., Raguso  C., et  al. Fat-free mass  change to  weight change ratio   during  refeeding following   lung   transplantation. Acta Diabetol. 2003;40Suppl1:S165–S167.</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Bachrach L.K. Dual energy X-ray absorptiometry (DEXA) measurements of bone density and body composition: promise and pitfalls // J. Pediatr. Endocrinol. Metab. – 2000. – Vol. 13, Suppl. 2. – S983–S988.</mixed-citation><mixed-citation xml:lang="en">Bachrach L.K. Dual energy X-ray absorptiometry (DEXA) measurements of bone  density and  body composition: promise and  pitfalls. J Pediatr Endocrinol Metab. 2000;13Suppl2:S983–S988.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
