nmpЖурнал им. Н.В. Склифосовского «Неотложная медицинская помощь»Russian Sklifosovsky Journal "Emergency Medical Care"2223-90222541-8017“N.V. Sklifosovsky Research Institute for Emergency Medicine”nmp-223Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWS OF LITERATURE«ПРОБЛЕМНЫЕ» ПОЛИРЕЗИСТЕНТНЫЕ БАКТЕРИИ — ВОЗБУДИТЕЛИ ВНУТРИБОЛЬНИЧНЫХ ИНФЕКЦИЙ У ПАЦИЕНТОВ В КРИТИЧЕСКИХ СОСТОЯНИЯХ (ОБЗОР ЛИТЕРАТУРЫ)THE “CHALLENGING” MULTIDRUG-RESISTANT PATHOGENS OF NOSOCOMIAL INFECTIONS IN CRITICALLY ILL PATIENTS (A LITERATURE REVIEW)ЧерненькаяТ. В.ChernenkayaT. V.

заведующая

научная лаборатория клинической микробиологии 

chernenkayat@rambler.ruГодковМ. А.GodkovM. A.НИИ скорой помощи им. Н.В. Склифосовского ДЗ г. Москвы, МоскваРоссияN.V. Sklifosovsky Researh Institute for Emergency Medicine, MoscowRussian Federation201503042016033035Copyright © Черненькая Т.В., Годков М.А., 20162016Черненькая Т.В., Годков М.А.Chernenkaya T.V., Godkov M.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jnmp.ru/jour/article/view/223

РЕЗЮМЕ. Изменение структуры основных возбудителей внутрибольничных инфекций и значительное распространение полирезистентных штаммов бактерий является естественным биологическим ответом на использование антибиотиков. Противомикробные препараты создают селективное давление, способствующее отбору, выживанию и размножению резистентных штаммов. В настоящем обзоре литературы представлена динамика структуры основных возбудителей внутрибольничных гнойно­септических инфекций и их устойчивости к антибиотикам за последние 70 лет. 

ABSTRACT. Changes in the structure of the main causative agents of nosocomial infections and significant spread of multidrug­resistant strains of bacteria are a natural biological response for antibiotics that selectively inhibit pathogens and contribute to selection, survival and growth of drug resistant strains of bacteria. In this literature review we present the change of structure of the major causative microorganisms of nosocomial septic infections and theirs resistance to antibiotics for the last 70 years. 

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The authors declare that there are no conflicts of interest present.