<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23934/2223-9022-2023-12-1-110-121</article-id><article-id custom-type="elpub" pub-id-type="custom">nmp-1576</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Хирургические методы стабилизации грудной клетки при множественных переломах ребер</article-title><trans-title-group xml:lang="en"><trans-title>Surgical Methods of Chest Stabilization in Multiple Rib Fractures</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1847-711X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарабрин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarabrin</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарабрин Евгений Александрович, доктор медицинских наук, заведующий кафедрой; главный научный сотрудник отделения неотложной хирургии, эндоскопии и интенсивной терапии</p><p>119991, Москва, ул. Большая Пироговская, д. 2, стр. 4</p><p>129090, Москва, Б. Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Evgeny A. Tarabrin, Doctor of Medical Sciences, Health Department, Head of the Department</p><p>2, bldg. 4, Bolshaya Pirogovskaya Str., Moscow, 119991</p><p>3, Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">t_evg_a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7838-4890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котанджян</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotanjyan</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котанджян Вазген Гагикович, заведующий хирургическим торакальным отделением</p><p>129090, Москва, Б. Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Vazgen G. Kotanjyan, Head of the Surgical Thoracic Department</p><p>3, Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">dr.kotanjan@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2170-0009</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Офицеров</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ofitserov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Офицеров Андрей Аркадьевич, научный сотрудник отделения биотехнологий и трансфузиологии</p><p>129090, Москва, Б. Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Andrey A. Ofitserov, Researcher</p><p>3, Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">3930590@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Торакальное хирургическое отделение, ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ; ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ»<country>Россия</country></aff><aff xml:lang="en">Surgical Thoracic Department, I.M. Sechenov First Moscow State Medical University of the Ministry; N.V. Sklifosovsky Research Institute for Emergency Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ»<country>Россия</country></aff><aff xml:lang="en">N.V. Sklifosovsky Research Institute for Emergency Medicine<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>16</day><month>04</month><year>2023</year></pub-date><volume>12</volume><issue>1</issue><fpage>110</fpage><lpage>121</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарабрин Е.А., Котанджян В.Г., Офицеров А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Тарабрин Е.А., Котанджян В.Г., Офицеров А.А.</copyright-holder><copyright-holder xml:lang="en">Tarabrin E.A., Kotanjyan V.G., Ofitserov A.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/1576">https://www.jnmp.ru/jour/article/view/1576</self-uri><abstract><p>Закрытая травма груди занимает одно из лидирующих мест среди всех повреждений. Переломы ребер могут приводить к формированию флотирующих фрагментов грудной стенки — «реберному клапану». При множественных переломах ребер с начала ХХ века использовались хирургические методы стабилизации грудной клетки, которые в последние десятилетия стали более популярными.  </p><p>Хирургическое лечение позволяет значительно уменьшить болевой синдром, ускорить восстановление респираторной функции и тем самым снизить частоту развития пневмонии, потребность в искусственной вентиляции легких и трахео­стомии и сократить период нахождения в стационаре. Различают четыре основные хирургические методики лечения, использующие: 1) тракцию грудной клетки; 2) аппараты внешней фиксации; 3) постоянную внутреннюю фиксацию; 4) накостный остеосинтез пластинами. В данном исследовании были дополнительно выделены методика, осуществляемая через торакоскопический доступ, и методика, использующая биоразлагаемые материалы. Хирургические возможности в лечении пациентов со множественными переломами ребер не исчерпаны и, вероятно, будут совершенствоваться по мере достижений в технологической сфере. </p></abstract><trans-abstract xml:lang="en"><p>Closed chest injury occupies one of the leading places among all injuries. Rib fractures can lead to the formation of floating fragments of the chest wall, the “costal valve”. With multiple rib fractures, surgical methods of chest stabilization have been used since the beginning of the 20th century, which have become more popular in recent decades.  </p><p>Surgical treatment can significantly reduce pain, accelerate the recovery of respiratory function. In turn, a decrease in pain reduces the incidence of pneumonia, the need for mechanical ventilation and tracheostomy, and the period of hospitalization. There are four main surgical methods of treatment: 1) chest traction methods; 2) external fixation devices; 3) methods of permanent internal fixation; 4) plate osteosynthesis. We also separated the group of techniques performed via thoracoscopic access and the technique using biodegradable materials. Surgical options in the treatment of patients with multiple rib fractures have not been exhausted and are likely to improve with advances in technology. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>остеосинтез ребер</kwd><kwd>закрытая травма груди</kwd><kwd>переломы ребер</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rib osteosynthesis</kwd><kwd>closed chest injury</kwd><kwd>rib fractures</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">LoCicero J, Mattox KL. Epidemiology of chest trauma. Surg Clin. 1989;69:15–19. PMID: 2911786 https://doi.org/10.1016/S0039- 6109(16)44730-4</mixed-citation><mixed-citation xml:lang="en">LoCicero J, Mattox KL. Epidemiology of chest trauma. Surg Clin. 1989;69:15–19. PMID: 2911786 https://doi.org/10.1016/S0039- 6109(16)44730-4</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Harrison M. Traumatic pneumothorax: a review of current practices. Br J Hosp Med. 2014;75:132–135. PMID: 24621627 https://doi.org/10.12968/ hmed.2014.75.3.132</mixed-citation><mixed-citation xml:lang="en">Harrison M. Traumatic pneumothorax: a review of current practices. Br J Hosp Med. 2014;75:132–135. PMID: 24621627 https://doi.org/10.12968/ hmed.2014.75.3.132</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Vana PG, Neubauer DC, Luchette FA. Contemporary management of flail chest. Am Surg. 2014;80:527–535. PMID: 24887787 https://doi. org/10.1177/000313481408000613</mixed-citation><mixed-citation xml:lang="en">Vana PG, Neubauer DC, Luchette FA. Contemporary management of flail chest. Am Surg. 2014;80:527–535. PMID: 24887787 https://doi. org/10.1177/000313481408000613</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Martin TJ, Eltorai AS, Dunn R, Varone А, Joyce MF, Kheirbeket T, al. Clinical management of rib fractures and methods for prevention of pulmonary complications: a review. Injury. 2019;50:1159–1165. PMID: 31047683 https://doi.org/10.1016/j.injury.2019.04.020</mixed-citation><mixed-citation xml:lang="en">Martin TJ, Eltorai AS, Dunn R, Varone А, Joyce MF, Kheirbeket T, al. Clinical management of rib fractures and methods for prevention of pulmonary complications: a review. Injury. 2019;50:1159–1165. PMID: 31047683 https://doi.org/10.1016/j.injury.2019.04.020</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">He WW, Yang Y, Wu WM, Zhao T, Guo X, Li Y, et al. Chest wall stabilization (CWS) in China: current situation and prospect. J Thorac Dis. 2019;11(Suppl 8):S1104–S1148. PMID: 31205761 https://doi. org/10.21037/jtd.2019.03.31</mixed-citation><mixed-citation xml:lang="en">He WW, Yang Y, Wu WM, Zhao T, Guo X, Li Y, et al. Chest wall stabilization (CWS) in China: current situation and prospect. J Thorac Dis. 2019;11(Suppl 8):S1104–S1148. PMID: 31205761 https://doi. org/10.21037/jtd.2019.03.31</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Познанский С.В. Евтихов Р.М., Кутырев Е.А., Колбашова Ю.Н., Кукушкин А.В. Видеоторакоскопическая стабилизация каркаса грудной клетки. Современные технологии в медицине. 2010;(1– 2):72–73.</mixed-citation><mixed-citation xml:lang="en">Poznanskiy SV, Evtikhov RM, Kutyrev EA, Kolbashova YuN, Kukushkin AV. Videotorakoskopicheskaya stabilizatsiya karkasa grudnoy kletki. Sovremennye tehnologii v medicine. 2010;(1–2):72–73 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bulger EM, Arneson MA, Mock CN, Jurkovich GJ. Rib fractures in the elderly. J Trauma. 2000;48:1040–1047. PMID: 10866248 https://doi. org/10.1097/00005373-200006000-00007</mixed-citation><mixed-citation xml:lang="en">Bulger EM, Arneson MA, Mock CN, Jurkovich GJ. Rib fractures in the elderly. J Trauma. 2000;48:1040–1047. PMID: 10866248 https://doi. org/10.1097/00005373-200006000-00007</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bemelman M, Poeze M, Blokhuis TJ, Leenen LPH. Historic overview of treatment techniques for rib fractures and flail chest. Eur J Trauma Emerg Surg. 2010;36:407–415. PMID: 21841952 https://doi.org/10.1007/ s00068-010-0046-5</mixed-citation><mixed-citation xml:lang="en">Bemelman M, Poeze M, Blokhuis TJ, Leenen LPH. Historic overview of treatment techniques for rib fractures and flail chest. Eur J Trauma Emerg Surg. 2010;36:407–415. PMID: 21841952 https://doi.org/10.1007/ s00068-010-0046-5</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Flagel BT, Luchette FA, Reed RL, Esposito TJ, Davis KA, Santaniello JM, et al. Half-a-dozen ribs: the breakpoint for mortality. Surgery. 2005;138:717–725. PMID: 16269301 https://doi.org/10.1016/ j.surg.2005.07.022</mixed-citation><mixed-citation xml:lang="en">Flagel BT, Luchette FA, Reed RL, Esposito TJ, Davis KA, Santaniello JM, et al. Half-a-dozen ribs: the breakpoint for mortality. Surgery. 2005;138:717–725. PMID: 16269301 https://doi.org/10.1016/ j.surg.2005.07.022</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Кукушкин М.Л., Табеева Г.Р., Подчуфарова Е.В. Болевой синдром: патофизиология, клиника, лечение. Москва: ИМАпресс; 2011.</mixed-citation><mixed-citation xml:lang="en">Kukushkin ML, Tabeeva GR, Podchufarova EV. Bolevoy sindrom: patofiziologiya, klinika, lechenie. Moscow: IMApress; 2011.(In Russ.) 11. May L, Hillermann C, Patil S. Rib fracture management. BJA Educ. 2016;16:26–32. https://doi.org/10.1093/bjaceaccp/mkv011</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">May L, Hillermann C, Patil S. Rib fracture management. BJA Educ. 2016;16:26–32. https://doi.org/10.1093/bjaceaccp/mkv011</mixed-citation><mixed-citation xml:lang="en">Van Lieshout EMM, Verhofstad MHJ, Van Silfhout DJT, Dubois EA. Diagnostic approach for myocardial contusion: a retrospective evaluation of patient data and review of the literature. Eur J Trauma Emerg Surg. 2021;47(4):1259–1272. PMID: 31982920 https://doi. org/10.1007/s00068-020-01305-4</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Van Lieshout EMM, Verhofstad MHJ, Van Silfhout DJT, Dubois EA. Diagnostic approach for myocardial contusion: a retrospective evaluation of patient data and review of the literature. Eur J Trauma Emerg Surg. 2021;47(4):1259–1272. PMID: 31982920 https://doi. org/10.1007/s00068-020-01305-4</mixed-citation><mixed-citation xml:lang="en">Bagnenko SF, Tulupov AN. Current Problems In Diagnostics and Treatment of Closed Chest Trauma. Emergency Medical Care. 2009;10(2):4–10. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Багненко С.Ф., Тулупов А.Н. Актуальные проблемы диагностики и лечения тяжелой закрытой травмы груди. Скорая медицинская помощь. 2009;10(2):4–10.</mixed-citation><mixed-citation xml:lang="en">Vagner EA, Rogatskiy VA, Chereshnev VA. Patologicheskaya fiziologiya travmy grudi. Perm’, 1990. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Вагнер Е.А., Рогацкий В.А., Черешнев В.А. Патологическая физиология травмы груди. Пермь; 1990.</mixed-citation><mixed-citation xml:lang="en">Velmahos GC, Vassiliu P, Chan LS, Murray JA, Berne TV, Demetriades D. Influence of flail chest on outcome among patients with severe thoracic cage trauma. Int Surg. 2002;87(4):240–244. PMID: 12575808</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Velmahos GC, Vassiliu P, Chan LS, Murray JA, Berne TV, Demetriades D. Influence of flail chest on outcome among patients with severe thoracic cage trauma. Int Surg. 2002;87(4):240–244. PMID: 12575808</mixed-citation><mixed-citation xml:lang="en">Dehghan N, De Mestral C, McKee MD, Schemitsch EH, Nathens A. Flail chest injuries: a review of outcomes and treatment practices from the National Trauma Data Bank. J Trauma Acute Care Surg. 2014;76(2):462– 468. PMID: 24458051 https://doi.org/10.1097/TA.0000000000000086</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Dehghan N, De Mestral C, McKee MD, Schemitsch EH, Nathens A. Flail chest injuries: a review of outcomes and treatment practices from the National Trauma Data Bank. J Trauma Acute Care Surg. 2014;76(2):462– 468. PMID: 24458051 https://doi.org/10.1097/TA.0000000000000086</mixed-citation><mixed-citation xml:lang="en">Moreno De La Santa P, Magdalena P, Polo Otero MD, Delgado C, Leal S, Trinidad C, et al. Rib fractures: mortality risk factors. Interact Cardiovasc Thorac Surg. 2013;17(Is suppl 1):19–20, abs 0-074. https:// doi.org/10.1093/icvts/ivt288.74</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Moreno De La Santa, Magdalena P, Polo Otero MD, Delgado C, Leal S, Trinidad C, et al. Rib fractures: mortality risk factors. Interact Cardiovasc Thorac Surg. 2013;17(Is suppl 1):19–20, abs 0–074. https:// doi.org/10.1093/icvts/ivt288.74</mixed-citation><mixed-citation xml:lang="en">Rendeki S, Molnár TF. Pulmonary contusion. J Thorac Dis. 2019;11(Suppl 2):S141–S151. PMID: 30906578 https://doi.org/10.21037/ jtd.2018.11.53</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rendeki S, Molnár TF. Pulmonary contusion. J Thorac Dis. 2019;11(Suppl 2): S141–S151. PMID: 30906578 https://doi. org/10.21037/jtd.2018.11.53</mixed-citation><mixed-citation xml:lang="en">Boyd AD. Lung injuries. In: Hood RM, Boyd AD, Culliford AT. (ed.) Thoracic Trauma. Philadelphia: Saunders; 1989:153–155.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Boyd AD. Lung injuries. In: Hood RM, Boyd AD, Culliford AT. (ed.) Thoracic Trauma. Philadelphia: Saunders; 1989. p. 153–155.</mixed-citation><mixed-citation xml:lang="en">Allen GS, Coates NE. Pulmonary contusion: A collective review. Am Surg. 1996;62:895–900. PMID: 8895709</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Allen GS, Coates NE. Pulmonary contusion: A collective review. Am Surg. 1996;62:895–900. PMID: 8895709</mixed-citation><mixed-citation xml:lang="en">Allen GS, Cox CS. Pulmonary contusion in children: Diagnosis and management. South Med J. 1998;91:1099–1106. PMID: 9853720 https:// doi.org/10.1097/00007611-199812000-00002</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Allen GS, Cox CS. Pulmonary contusion in children: Diagnosis and management. South Med J. 1998;91:1099–1106. PMID: 9853720 https:// doi.org/10.1097/00007611-199812000-00002</mixed-citation><mixed-citation xml:lang="en">Ganie FA, Lone H, Lone GN, Wani ML, Singh S, Dar AM, et al. Lung Contusion: A Clinico-Pathological Entity with Unpredictable Clinical Course. Bull Emerg Trauma. 2013;1:7–16. PMID: 27162815</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ganie FA, Lone H, Lone GN, Wani ML, Singh S, Dar AM, et al. Lung Contusion: A Clinico-Pathological Entity with Unpredictable Clinical Course. Bull Emerg Trauma. 2013;1:7–16. PMID: 27162815</mixed-citation><mixed-citation xml:lang="en">Cohn SM. Pulmonary contusion: Review of the clinical entity. J Trauma. 1997;42:973–979. PMID: 9191684 https://doi.org/10.1097/00005373- 199705000-00033</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Cohn SM. Pulmonary contusion: Review of the clinical entity. J Trauma. 1997;42:973–979. PMID: 9191684 https://doi.org/10.1097/00005373- 199705000-00033</mixed-citation><mixed-citation xml:lang="en">Livingston DH, Hauser CJ. Trauma to the chest wall and lung. McGrawHill Professional, 2003. In: Moore EE, Feliciano DV, Mattox KL. (eds.) Trauma. 5th ed. New York, McGraw-Hill Professional; 2004:507–538.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Livingston DH, Hauser CJ. Trauma to the chest wall and lung. McGrawHill Professional, 2003. In: Moore EE, Feliciano DV, Mattox KL. (eds.) Trauma. 5th ed. New York, McGraw-Hill Professional; 2004. p. 507– 538.</mixed-citation><mixed-citation xml:lang="en">Bader A, Rahman U, Morris M, McCormack JE, Huang EC, Zawin M, et al. Pulmonary contusions in the elderly after blunt trauma: incidence and outcomes. J Surg Res. 2018;230:110–116. PMID: 30100025 https://doi. org/10.1016/j.jss.2018.04.049</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Bader A, Rahman U, Morris M, McCormack JE, Huang EC, Zawin M, et al. Pulmonary contusions in the elderly after blunt trauma: incidence and outcomes. J Surg Res. 2018;230:110–116. PMID: 30100025 https://doi. org/10.1016/j.jss.2018.04.049</mixed-citation><mixed-citation xml:lang="en">Haynes D, Baumann M. Management of pneumothorax. Semin Respir Crit Care Med. 2010;31:769–780. PMID: 21213209 https://doi.org/10.1055/ s-0030-1269837</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Haynes D, Baumann M. Management of pneumothorax. Semin Respir Crit Care Med. 2010;31:769–780. PMID: 21213209 https://doi.org/10.1055/ s-0030-1269837</mixed-citation><mixed-citation xml:lang="en">Ramanathan R, Wolfe LG, Duane TM. Initial suction evacuation of traumatic hemothoraces: a novel approach to decreasing chest tube duration and complications. Am Surg. 2012;78:883–887. PMID: 22856496</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Ramanathan R, Wolfe LG, Duane TM. Initial suction evacuation of traumatic hemothoraces: a novel approach to decreasing chest tube duration and complications. Am Surg. 2012;78:883–887. PMID: 22856496</mixed-citation><mixed-citation xml:lang="en">Athanassiadi K, Gerazounis M, Theakos N. Management of 150 flail chest injuries: analysis of risk factors affecting outcome. Eur J Cardiothorac Surg. 2004;26:373–376. PMID: 15296899 https://doi. org/10.1016/j.ejcts.2004.04.011</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Athanassiadi K, Gerazounis M, Theakos N. Management of 150 flail chest injuries: analysis of risk factors affecting outcome. Eur J Cardiothorac Surg. 2004;26:373–376. PMID: 15296899 https://doi. org/10.1016/j.ejcts.2004.04.011</mixed-citation><mixed-citation xml:lang="en">Karmy-Jones R, Jurkovich G. Management of Blunt Chest and Diaphragm Injuries. In: Patterson GA, Pearson FG, Cooper JD, Deslauriers J, Luketich JD, Lerut AEMR. (eds.) Pearson’s Thoracic and Esophageal Surgery. 3rd ed. Phiadelphia, PA: Churchill Livingston Elsevier; 2008:1768–1776.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Karmy-Jones R, Jurkovich G. Management of Blunt Chest and Diaphragm Injuries. In: Patterson GA, Pearson FG, Cooper JD, Deslauriers J, Luketich JD, Lerut AEMR. (eds.) Pearson’s Thoracic and Esophageal Surgery. 3rd ed. Phiadelphia, PA: Churchill Livingston Elsevier; 2008. p. 1768–1776.</mixed-citation><mixed-citation xml:lang="en">Liu Q, Luan L, Zhang G, Li B. Treatment of Chronic Traumatic Diaphragmatic Hernia Based on Laparoscopic Repair: Experiences From 23 Cases. Front Surg. 2021;8:706824. PMID: 34336921 https://doi. org/10.3389/fsurg.2021.706824</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Q, Luan L, Zhang G, Li B. Treatment of Chronic Traumatic Diaphragmatic Hernia Based on Laparoscopic Repair: Experiences From 23 Cases. Front Surg. 2021;8:706824. PMID: 34336921 https://doi. org/10.3389/fsurg.2021.706824</mixed-citation><mixed-citation xml:lang="en">Tessely H, Journé S, Therasse A, Hossey D., Lemaitre J. A case of colon necrosis resulting from a delayed traumatic diaphragmatic hernia. J Surg Case Rep. 2020;2020:rjaa101. PMID: 32582428 https://doi. org/10.1093/jscr/rjaa101</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Tessely H, Journé S, Therasse A, Hossey D., Lemaitre J. A case of colon necrosis resulting from a delayed traumatic diaphragmatic hernia. J Surg Case Rep. 2020;2020:rjaa101. PMID: 32582428 https://doi. org/10.1093/jscr/rjaa101</mixed-citation><mixed-citation xml:lang="en">Granetzny A, Abd El-Aal M, Emam E, Shalaby A, Boseila A. Surgical versus conservative treatment of flail chest. Evaluation of the pulmonary status. Interact Cardiovasc Thorac Surg. 2005;4(6):583–587. PMID: 17670487 https://doi.org/10.1510/icvts.2005.111807</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Granetzny A, Abd El-Aal M, Emam E, Shalaby A, Boseila A. Surgical versus conservative treatment of flail chest. Evaluation of the pulmonary status. Interact Cardiovasc Thorac Surg. 2005;4(6):583–587. PMID: 17670487 https://doi.org/10.1510/icvts.2005.111807</mixed-citation><mixed-citation xml:lang="en">Richter T, Ragaller M. Ventilation in chest trauma. J Emerg Trauma.Shock. 2011;4(2):251–259. PMID: 21769213 https://doi.org/10.4103/0974- 2700.82215</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Richter T, Ragaller M. Ventilation in chest trauma. J Emerg Trauma. Shock. 2011;4(2):251–259. PMID: 21769213 https://doi.org/10.4103/0974- 2700.82215</mixed-citation><mixed-citation xml:lang="en">Duggal A, Perez P, Golan E, Tremblay L, Sinuff T. Safety and efficacy of noninvasive ventilation in patients with blunt chest trauma: a systematic review. Crit Care. 2013;17(4):R142. PMID: 23876230 https:// doi.org/10.1186/cc12821</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Duggal A, Perez P, Golan E, Tremblay L, Sinuff T. Safety and efficacy of noninvasive ventilation in patients with blunt chest trauma: a systematic review. Crit Care. 2013;17(4):R142. PMID: 23876230 https:// doi.org/10.1186/cc12821</mixed-citation><mixed-citation xml:lang="en">Benyan AS. Vnutrennyaya pnevmaticheskaya stabilizatsiya v lechenii perednego rebernogo klapana. Messenger of Anesthesiology and Resuscitation. 2014;(6):66–68. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Бенян А.С. Внутренняя пневматическая стабилизация в лечении переднего реберного клапана. Вестник анестезиологии и реаниматологии. 2014;(6):66–68.</mixed-citation><mixed-citation xml:lang="en">Cullen P, Modell JH, Kirby RR, Klein Jr EF, Long W. Treatment of flail chest. Arch Surg. 1975;110:1099–1103. PMID: 1098616 https://doi. org/10.1001/archsurg.1975.01360150043008</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Cullen P, Modell JH, Kirby RR, Klein Jr EF, Long W. Treatment of flail chest. Arch Surg. 1975;110:1099–1103. PMID: 1098616 https://doi. org/10.1001/archsurg.1975.01360150043008</mixed-citation><mixed-citation xml:lang="en">Fowler TT, Taylor BC, Bellino MJ, Althausen PL. Surgical Treatment of Flail Chest and Rib Fractures. J Am Acad Orthop Surg. 2014;22(12):751– 760. PMID: 25425610 https://doi.org/10.5435/JAAOS-22-12-751</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Fowler TT, Taylor BC, Bellino MJ, Althausen PL. Surgical Treatment of Flail Chest and Rib Fractures. J Am Acad Orthop Surg. 2014;22(12):751– 760. PMID: 25425610 https://doi.org/10.5435/JAAOS-22-12-751</mixed-citation><mixed-citation xml:lang="en">Leinicke JA, Elmore L, Freeman BD, Colditz GA. Operative Management of Rib Fractures in the Setting of Flail Chest: A Systematic Review and Meta-Analysis. Ann Surg. 2013; 258(6):914–921. PMID: 23511840 https://doi.org/10.1097/SLA.0b013e3182895bb0</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Leinicke JA, Elmore L, Freeman BD, Colditz GA. Operative Management of Rib Fractures in the Setting of Flail Chest: A Systematic Review and Meta-Analysis. Ann Surg. 2013; 258(6):914–921. PMID: 23511840 https://doi.org/10.1097/SLA.0b013e3182895bb0</mixed-citation><mixed-citation xml:lang="en">Benyan AS. Surgical Stabilization of the Chest in Multiple and Floating Rib Fractures. N.N. Priorov Journal of Traumatology and Orthopedics. 2015;22(3):86–92. (In Russ.) https://doi.org/10.17816/vto201522386-92.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Бенян А.С. Хирургическая стабилизация грудной клетки при множественных и флотирующих переломах ребер. Вестник травматологии и ортопедии им.Н.Н. Приорова. 2015;(3):86–92.</mixed-citation><mixed-citation xml:lang="en">Jones T, Richardson E. Traction on the sternum in the treatment of multiple fractured ribs. Surg Gynec Obstet. 1926;42:283.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Jones T, Richardson E. Traction on the sternum in the treatment of multiple fractured ribs. Surg Gynec Obstet. 1926;42:283.</mixed-citation><mixed-citation xml:lang="en">Jasloiv I. Skeletal traction in the treatment of multiple fractures of the thoracic cage. Am J Surg. 1946;72(5):753–755. PMID: 21003141 https:// doi.org/10.1016/0002-9610(46)90358-3</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Jasloiv I. Skeletal traction in the treatment of multiple fractures of the thoracic cage. Am J Surg. 1946;72(5):753–755. PMID: 21003141 https:// doi.org/10.1016/0002-9610(46)90358-3</mixed-citation><mixed-citation xml:lang="en">Heroy WW, Eggleston FC. A method of skeletal traction applied through the sternum in «steering wheel» injury of the chest. Ann Surg. 1951;133(1):135–138. PMID: 14800268 https://doi. org/10.1097/00000658-195101000-00016</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Heroy WW, Eggleston FC. A method of skeletal traction applied through the sternum in «steering wheel» injury of the chest. Ann Surg. 1951;133(1):135–138. PMID: 14800268 https://doi. org/10.1097/00000658-195101000-00016</mixed-citation><mixed-citation xml:lang="en">Constantinescu O. A new method of treating the flaii chest wall. Am J Surg. 1965;109:604–610. PMID: 14281884 https://doi.org/10.1016/ s0002-9610(65)80014-9</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Constantinescu O. A new method of treating the flaii chest wall. Am J Surg. 1965;109:604–610. PMID: 14281884 https://doi.org/10.1016/ s0002-9610(65)80014-9</mixed-citation><mixed-citation xml:lang="en">Kornilov NV, Gryaznukhin EG. Travmatologiya i ortopediya. Saint Petersburg, 2004. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Корнилов Н.В., Грязнухин Э.Г. Травматология и ортопедия. Санкт-Петербург; 2004.</mixed-citation><mixed-citation xml:lang="en">Balci AE, Eren S, Cakir О, Eren MN. Open fixation in flail chest: review of 64 patients. Asian Cardiovasc Thorac Ann. 2004;12(1):11–15. PMID: 14977734 https://doi.org/10.1177/021849230401200104</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Balci AE, Eren S, Cakir О, Eren MN. Open fixation in flail chest: review of 64 patients. Asian Cardiovasc Thorac Ann. 2004;12(1):11–15. PMID: 14977734 https://doi.org/10.1177/021849230401200104</mixed-citation><mixed-citation xml:lang="en">Ushakov NG. The algorithm of diagnostics and tactics of treatment of victims with the multiple ribs fracture at the closed chest injury. Aspirantskiy Vestnik Povolzhiya. 2010;10(3–4):116–119. (In Russ.) https://doi.org/10.17816/2072-2354.2010.0.3-4.116-119</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Ушаков Н.Г. Алгоритм диагностики и тактики лечения пострадавших с множественными клапанными переломами ребер при закрытой травме груди. Аспирантский вестник Поволжья. 2010;(3– 4):116–119.</mixed-citation><mixed-citation xml:lang="en">Goloboro’dko NK, Bulaga VV. General principles of the activities of a specialized center of polytrauma and shock. Grekov’s Bulletin of Surgery. 1989;142(6):139–141. PMID: 2815465. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Голобородько H.K., Булага В.В. Общие принципы работы специализированного центра политравмы и шока. Вестник хирургии им. И.И. Грекова. 1989;(6):139–141.</mixed-citation><mixed-citation xml:lang="en">Gredzhev AF, Paniotov AP. Panel’naya fiksatsiya pri mnozhestvennykh perelomakh reber. Klinicheskaia khirurgiia. 1977;(8):69–78. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Греджев А.Ф., Паниотов А.П. Панельная фиксация при множественных переломах ребер. Клиническая хирургия. 1977;(8):69–78.</mixed-citation><mixed-citation xml:lang="en">Glavas M, Altarac S, Vukas D, Ivancic A, Drazinic I, Gusic N, et al. Flail chest stabilization with palacos prosthesis. Acta Med Croatica. 2001;55(2):91–95. PMID: 11505635</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Glavas M, Altarac S, Vukas D, Ivancic A, Drazinic I, Gusic N, et al. Flail chest stabilization with palacos prosthesis. Acta Med Croatica. 2001;55(2):91–95. PMID: 11505635</mixed-citation><mixed-citation xml:lang="en">Vishnevskiy DA, Rudakov CC, Milanov NO. Khirurgiya grudnoy stenki. Moscow: Vidar-M Publ.; 2005. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Вишневский Д.А., Рудаков C.C., Миланов Н.O. Хирургия грудной стенки. Москва: Видар-М; 2005. 51. Шатохин В.Д., Пушкин С.Ю., Дьячкова Г.В., Губа А.Д., Шатохин Д.В., Камеев И.Р. Результаты оперативного лечения флотирующих переломов грудинно-реберного комплекса. Гений ортопедии. 2018;24(3):290–295.</mixed-citation><mixed-citation xml:lang="en">Shatokhin VD, Pushkin SYu, Diachkova GV, Guba AD, Shatokhin DV, Kameev IR. Outcomes of operative treatment of floating sternocostal fractures. Genij Ortopedii. 2018;24(3):290–295. https://doi. org/10.18019/1028-4427-2018-24-3-290-295</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Dor V, Paoli J, Noirclerc M, Malmejac C, Chauvin G, Pons R. Lysteosynthese des volets thoraciques technique, resultants et indications apropos de 19 observations. Ann Chir. 1967;2(15):983–996. PMID: 5619289</mixed-citation><mixed-citation xml:lang="en">Dor V, Paoli J, Noirclerc M, Malmejac C, Chauvin G, Pons R. Lysteosynthese des volets thoraciques technique, resultants et indications apropos de 19 observations. Ann Chir. 1967;2(15):983–996. PMID: 5619289</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Guernelli N, Bragaglia RB, Briccoli A, Mastrorilli M, Vecchi R. Technique for the management of anterior flail chest. Thorax. 1979;34(2):247–248. PMID: 483193 https://doi.org/10.1136/thx.34.2.247</mixed-citation><mixed-citation xml:lang="en">Guernelli N, Bragaglia RB, Briccoli A, Mastrorilli M, Vecchi R. Technique for the management of anterior flail chest. Thorax. 1979;34(2):247–248. PMID: 483193 https://doi.org/10.1136/thx.34.2.247</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Landreneau RS, Hinson JM, Hazerlrigg SR, Johnson JA, Boley TB, Curtis JJ. Strut fixation of an extensive flail chest. Ann Thorac Surg. 1991;51(3):473–475. PMID: 1998429 https://doi.org/10.1016/0003- 4975(91)90871-m</mixed-citation><mixed-citation xml:lang="en">Landreneau RS, Hinson JM, Hazerlrigg SR, Johnson JA, Boley TB, Curtis JJ. Strut fixation of an extensive flail chest. Ann Thorac Surg. 1991;51(3):473–475. PMID: 1998429 https://doi.org/10.1016/0003- 4975(91)90871-m</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Шaпoт Ю.Б., Бесаев Г.М., Кашанский Ю.Б., Зайцев E.H. Техника остеосинтеза при переломах ребер, грудины и ключицы. Вестник хирургии им. И.И. Грекова. 1985;(11):83–87.</mixed-citation><mixed-citation xml:lang="en">Шaпoт Ю.Б., Бесаев Г.М., Кашанский Ю.Б., Зайцев E.H. Техника остеосинтеза при переломах ребер, грудины и ключицы. Вестник хирургии им. И.И. Грекова. 1985;(11):83–87.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Forward DP, Ollivere BJ, Ng JWG, Coughlin TA, Rollins KE. Current concepts in rib fracture fixation. Bone Jt. 360. 2016;5(5):2–7. https://doi. org/10.1302/2048-0105.55.360464</mixed-citation><mixed-citation xml:lang="en">Forward DP, Ollivere BJ, Ng JWG, Coughlin TA, Rollins KE. Current concepts in rib fracture fixation. Bone Jt. 360. 2016;5(5):2–7. https://doi. org/10.1302/2048-0105.55.360464</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Bottlang M, Helzel I, Long W, Fitzpatrick D, Madey S. Less-Invasive Stabilization of Rib Fractures by Intramedullary Fixation: A Biomechanical Evaluation. J Trauma. 2010;68(5):1218–1224. PMID: 20068479 https://doi.org/10.1097/TA.0b013e3181bb9df1</mixed-citation><mixed-citation xml:lang="en">Bottlang M, Helzel I, Long W, Fitzpatrick D, Madey S. Less-Invasive Stabilization of Rib Fractures by Intramedullary Fixation: A Biomechanical Evaluation. J Trauma. 2010;68(5):1218–1224. PMID: 20068479 https://doi.org/10.1097/TA.0b013e3181bb9df1</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Bottlang M, Walleser S, Noll M, Honold S, Madey SM, Fitzpatrick D, et al. Biomechanical rationale and evaluation of an implant system for rib fracture fixation. Eur J Trauma Emerg Surg. 2010;36(5):417–426. PMID: 21841953 https://doi.org/10.1007/s00068-010-0047-4</mixed-citation><mixed-citation xml:lang="en">Bottlang M, Walleser S, Noll M, Honold S, Madey SM, Fitzpatrick D, et al. Biomechanical rationale and evaluation of an implant system for rib fracture fixation. Eur J Trauma Emerg Surg. 2010;36(5):417–426. PMID: 21841953 https://doi.org/10.1007/s00068-010-0047-4</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Zaidenberg EE, Rossi LA, Bongiovanni SL, Tanoira I, Maignon G, Ranalletta M. Snapping scapular syndrome secondary to rib intramedullary fixation device. Int J Surg Case Rep. 2015;17:158–160. PMID: 26629853 https://doi.org/10.1016/j.ijscr.2015.11.010</mixed-citation><mixed-citation xml:lang="en">Zaidenberg EE, Rossi LA, Bongiovanni SL, Tanoira I, Maignon G, Ranalletta M. Snapping scapular syndrome secondary to rib intramedullary fixation device. Int J Surg Case Rep. 2015;17:158–160. PMID: 26629853 https://doi.org/10.1016/j.ijscr.2015.11.010</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Akil A, Ziegeler S, Reichelt J, Semik M, Müller MC, Fischer S. Rib osteosynthesis is a safe and effective treatment and leads to a significant reduction of trauma associated pain. Eur J Trauma Emerg Surg. PMID: 30989244 https://doi.org/10.1007/s00068-018-01062-5</mixed-citation><mixed-citation xml:lang="en">Akil A, Ziegeler S, Reichelt J, Semik M, Müller MC, Fischer S. Rib osteosynthesis is a safe and effective treatment and leads to a significant reduction of trauma associated pain. Eur J Trauma Emerg Surg. PMID: 30989244 https://doi.org/10.1007/s00068-018-01062-5</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Redwan B, Reichelt J, Freermann S, Semik M, Fischer S. Video-assisted minimally invasive rib osteosynthesis using intramedullary titanium splints in patients with unstable rib fractures: treatment algorithm and first clinical results. Interact Cardiovasc Thorac Surg. 2015;21(Suppl 1): S60. https://doi.org/10.1093/icvts/ivv204.220</mixed-citation><mixed-citation xml:lang="en">Redwan B, Reichelt J, Freermann S, Semik M, Fischer S. Video-assisted minimally invasive rib osteosynthesis using intramedullary titanium splints in patients with unstable rib fractures: treatment algorithm and first clinical results. Interact Cardiovasc Thorac Surg. 2015;21(Suppl 1): S60. https://doi.org/10.1093/icvts/ivv204.220</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">De Jong MB, Kokke MC, Hietbrink F, Leenen LPH. Surgical Management of Rib Fractures: Strategies and Literature Review. Scand J Surg. 2014;103(2):120–125. PMID: 24782038 https://doi.org/10.1177/145749 6914531928</mixed-citation><mixed-citation xml:lang="en">De Jong MB, Kokke MC, Hietbrink F, Leenen LPH. Surgical Management of Rib Fractures: Strategies and Literature Review. Scand J Surg. 2014;103(2):120–125. PMID: 24782038 https://doi.org/10.1177/145749 6914531928</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Marasco S, Quayle M, Summerhayes R, Šutalo ID, Liovic P. An assessment of outcomes with intramedullary fixation of fractured ribs. J Cardiothorac Surg. 2016;11(1):126. PMID: 27495253 https://doi. org/10.1186/s13019-016-0510-3</mixed-citation><mixed-citation xml:lang="en">Marasco S, Quayle M, Summerhayes R, Šutalo ID, Liovic P. An assessment of outcomes with intramedullary fixation of fractured ribs. J Cardiothorac Surg. 2016;11(1):126. PMID: 27495253 https://doi. org/10.1186/s13019-016-0510-3</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Pharaon KS, Marasco S, Mayberry J. Rib Fractures, Flail Chest, and Pulmonary Contusion. Curr Trauma Rep. 2015;1:237–242. https://doi. org/10.1007/s40719-015-0026-7</mixed-citation><mixed-citation xml:lang="en">Pharaon KS, Marasco S, Mayberry J. Rib Fractures, Flail Chest, and Pulmonary Contusion. Curr Trauma Rep. 2015;1:237–242. https://doi. org/10.1007/s40719-015-0026-7</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Бенян А.С., Пушкин С.Ю., Сызранцев Ю.В., Камеев И.Р. Остеосинтез ребер с применением технологии «MATRIX RIB» в лечении пострадавшего с множественными флотирующими переломами ребер. Вестник хирургии им.И.И. Грекова. 2013;172(6):78–79.</mixed-citation><mixed-citation xml:lang="en">Бенян А.С., Пушкин С.Ю., Сызранцев Ю.В., Камеев И.Р. Остеосинтез ребер с применением технологии «MATRIX RIB» в лечении пострадавшего с множественными флотирующими переломами ребер. Вестник хирургии им.И.И. Грекова. 2013;172(6):78–79.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Pushkin S, Benyan A. Our first steps in osteosynthesis of fractured ribs using Matrix Rib technologies. Eur Respir J. 2012;40(Suppl 56): Annual Congress 2012: Chest wall, thoracic trauma and complications in thoracic surgery. Thematic Poster Session, #2421. URL: https://www. ers-education.org/lr/show-details/?idP=120960 [Дата обращения 13 мая 2022 г.]</mixed-citation><mixed-citation xml:lang="en">Pushkin S, Benyan A. Our first steps in osteosynthesis of fractured ribs using Matrix Rib technologies. Eur Respir J. 2012;40(Suppl 56): Annual Congress 2012: Chest wall, thoracic trauma and complications in thoracic surgery. Thematic Poster Session, #2421. URL: https://www. ers-education.org/lr/show-details/?idP=120960 [Дата обращения 13 мая 2022 г.]</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Bottlang M, Long WB, Phelan D, Fielder D, Madey SM. Surgical stabilization of flail chest injuries with MatrixRIB implants: A prospective observational study. Injury. 2013;44(2):232–238. PMID: 22910817 https://doi.org/10.1016/j.injury.2012.08.011</mixed-citation><mixed-citation xml:lang="en">Bottlang M, Long WB, Phelan D, Fielder D, Madey SM. Surgical stabilization of flail chest injuries with MatrixRIB implants: A prospective observational study. Injury. 2013;44(2):232–238. PMID: 22910817 https://doi.org/10.1016/j.injury.2012.08.011</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Wu W-M, Yang Y, Gao Z-L, Zhao T-C, He W-W. Which is better to multiple rib fractures, surgical treatment or conservative treatment? Int J Clin Exp Med. 2015;8(5):7930–7936. PMID: 26221350</mixed-citation><mixed-citation xml:lang="en">Wu W-M, Yang Y, Gao Z-L, Zhao T-C, He W-W. Which is better to multiple rib fractures, surgical treatment or conservative treatment? Int J Clin Exp Med. 2015;8(5):7930–7936. PMID: 26221350</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Jermin PJ, Perry J, Kalra S, Flockton E, Rourke HK. The Use of Novel Adopters for Acute Rib Fixation in Critical Chest Trauma, Undertaken by Orthopaedic Surgeons: an Observational Cohort Study. J Crit Care Med. 2015;1(3):96–101. https://doi.org/10.1515/jccm-2015-0016</mixed-citation><mixed-citation xml:lang="en">Jermin PJ, Perry J, Kalra S, Flockton E, Rourke HK. The Use of Novel Adopters for Acute Rib Fixation in Critical Chest Trauma, Undertaken by Orthopaedic Surgeons: an Observational Cohort Study. J Crit Care Med. 2015;1(3):96–101. https://doi.org/10.1515/jccm-2015-0016</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Pieracci FM, Lin Y, Rodil M, Synder M, Herbert B, Kha Tran D, et al. A prospective, controlled clinical evaluation of surgical stabilization of severe rib fractures. J Trauma Acute Care Surg. 2016;80(2):187–194. PMID: 26595710 https://doi.org/10.1097/TA.0000000000000925</mixed-citation><mixed-citation xml:lang="en">Pieracci FM, Lin Y, Rodil M, Synder M, Herbert B, Kha Tran D, et al. A prospective, controlled clinical evaluation of surgical stabilization of severe rib fractures. J Trauma Acute Care Surg. 2016;80(2):187–194. PMID: 26595710 https://doi.org/10.1097/TA.0000000000000925</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Xu JQ, Qiu PL, Yu RG, Gong SR, Ye Y, Shang XL. Better short-term efficacy of treating severe flail chest with internal fixation surgery compared with conservative treatments. Eur J Med Res. 2015;20(1):55. PMID: 26003405 https://doi.org/10.1186/s40001-015-0146-0</mixed-citation><mixed-citation xml:lang="en">Xu JQ, Qiu PL, Yu RG, Gong SR, Ye Y, Shang XL. Better short-term efficacy of treating severe flail chest with internal fixation surgery compared with conservative treatments. Eur J Med Res. 2015;20(1):55. PMID: 26003405 https://doi.org/10.1186/s40001-015-0146-0</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Qiu M, Shi Z, Xiao J, Zhang X, Ling S, Ling H. Potential Benefits of Rib Fracture Fixation in Patients with Flail Chest and Multiple Non-flail Rib Fractures. Indian J Surg. 2016;78(6):458–463. PMID: 28100942 https:// doi.org/10.1007/s12262-015-1409-2</mixed-citation><mixed-citation xml:lang="en">Qiu M, Shi Z, Xiao J, Zhang X, Ling S, Ling H. Potential Benefits of Rib Fracture Fixation in Patients with Flail Chest and Multiple Non-flail Rib Fractures. Indian J Surg. 2016;78(6):458–463. PMID: 28100942 https:// doi.org/10.1007/s12262-015-1409-2</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Althausen PL, Shannon S, Watts C, Thomas K, Bain MA, Coll D, et al. Early surgical stabilization of flail chest with locked plate fixation. J Orthop Trauma. 2011;25(11):641–647 PMID: 22008858 https://doi. org/10.1097/BOT.0b013e318234d479</mixed-citation><mixed-citation xml:lang="en">Althausen PL, Shannon S, Watts C, Thomas K, Bain MA, Coll D, et al. Early surgical stabilization of flail chest with locked plate fixation. J Orthop Trauma. 2011;25(11):641–647 PMID: 22008858 https://doi. org/10.1097/BOT.0b013e318234d479</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Beks RB, Reetz D, de Jong MB, Groenwold RHH, Hietbrink F, Edwards MJR, et al. Rib fixation versus non-operative treatment for flail chest and multiple rib fractures after blunt thoracic trauma: a multicenter cohort study. Eur J Trauma Emerg Surg. 2019;45(4):655–663. PMID: 30341561 https://doi.org/10.1007/s00068-018-1037-1</mixed-citation><mixed-citation xml:lang="en">Beks RB, Reetz D, de Jong MB, Groenwold RHH, Hietbrink F, Edwards MJR, et al. Rib fixation versus non-operative treatment for flail chest and multiple rib fractures after blunt thoracic trauma: a multicenter cohort study. Eur J Trauma Emerg Surg. 2019;45(4):655–663. PMID: 30341561 https://doi.org/10.1007/s00068-018-1037-1</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Ng CSH, Wong RHL, Kwok MWT, Yim APC. Delayed fracture of MatrixRIB precontoured plate system. Interact Cardiovasc Thorac Surg. 2014;19(3):512–514. PMID: 24876218 https://doi.org/10.1093/icvts/ ivu175</mixed-citation><mixed-citation xml:lang="en">Ng CSH, Wong RHL, Kwok MWT, Yim APC. Delayed fracture of MatrixRIB precontoured plate system. Interact Cardiovasc Thorac Surg. 2014;19(3):512–514. PMID: 24876218 https://doi.org/10.1093/icvts/ ivu175</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">De Palma A, Sollitto F, Loizzi D, Di Gennaro F, Scarascia D, Carlucci A, et al. Chest wall stabilization and reconstruction: short and longterm results 5 years after the introduction of a new titanium plates system. J Thorac Dis. 2016;8(3):490–498. PMID: 27076945 https://doi. org/10.21037/jtd.2016.02.64</mixed-citation><mixed-citation xml:lang="en">De Palma A, Sollitto F, Loizzi D, Di Gennaro F, Scarascia D, Carlucci A, et al. Chest wall stabilization and reconstruction: short and longterm results 5 years after the introduction of a new titanium plates system. J Thorac Dis. 2016;8(3):490–498. PMID: 27076945 https://doi. org/10.21037/jtd.2016.02.64</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Sales JR, Ellis TJ, Gillard J, Liu Q, Chen JC, Ham B, Mayberry JC. Biomechanical Testing of a Novel, Minimally Invasive Rib Fracture Plating System. J Trauma Inj Infect Crit Care. 2008;64(5):1270–1274. PMID: 18469649 https://doi.org/10.1097/TA.0b013e31804a7fd5</mixed-citation><mixed-citation xml:lang="en">Sales JR, Ellis TJ, Gillard J, Liu Q, Chen JC, Ham B, Mayberry JC. Biomechanical Testing of a Novel, Minimally Invasive Rib Fracture Plating System. J Trauma Inj Infect Crit Care. 2008;64(5):1270–1274. PMID: 18469649 https://doi.org/10.1097/TA.0b013e31804a7fd5</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Deb SJ. Rib Fracture Stabilization Reduces Chest Wall Pain following Blunt Thoracic Trauma. J Trauma Treat. 2014;S2:1–4. https://doi. org/10.4172/2167-1222.S2-004</mixed-citation><mixed-citation xml:lang="en">Deb SJ. Rib Fracture Stabilization Reduces Chest Wall Pain following Blunt Thoracic Trauma. J Trauma Treat. 2014;S2:1–4. https://doi. org/10.4172/2167-1222.S2-004</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Said SM, Goussous N, Zielinski MD, Schiller HJ, Kim BD. Surgical stabilization of flail chest: the impact on postoperative pulmonary function. Eur J Trauma Emerg Surg. 2014;40(4):501–505. PMID: 26816247 https://doi.org/10.1007/s00068-013-0344-9</mixed-citation><mixed-citation xml:lang="en">Said SM, Goussous N, Zielinski MD, Schiller HJ, Kim BD. Surgical stabilization of flail chest: the impact on postoperative pulmonary function. Eur J Trauma Emerg Surg. 2014;40(4):501–505. PMID: 26816247 https://doi.org/10.1007/s00068-013-0344-9</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Petscavage JM, Ha AS, Khorashadi L, Perrich K, Chew FS. New and Improved Orthopedic Hardware for the 21st Century: Part 2, Lower Extremity and Axial Skeleton. Am J Roentgenol. 2011;197(3):W434–444. PMID: 21862770 https://doi.org/ 10.2214/AJR.10.5354</mixed-citation><mixed-citation xml:lang="en">Petscavage JM, Ha AS, Khorashadi L, Perrich K, Chew FS. New and Improved Orthopedic Hardware for the 21st Century: Part 2, Lower Extremity and Axial Skeleton. Am J Roentgenol. 2011;197(3):W434–444. PMID: 21862770 https://doi.org/ 10.2214/AJR.10.5354</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Judet R. Costal osteosynthesis. Rev Chir Orthop Reparatrice Appar Mot. 1973;59(Suppl 1):334–335. PMID: 4268839</mixed-citation><mixed-citation xml:lang="en">Judet R. Costal osteosynthesis. Rev Chir Orthop Reparatrice Appar Mot. 1973;59(Suppl 1):334–335. PMID: 4268839</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Jayle CP, Allain G, Ingrand P, Laksiri L, Bonnin E, Hajj-Chahine J, et al. Flail Chest in Polytraumatized Patients: Surgical Fixation Using Stracos Reduces Ventilator Time and Hospital Stay. Biomed Res Int. 2015;2015: 624723. PMID: 25710011 https://doi.org/10.1155/2015/624723</mixed-citation><mixed-citation xml:lang="en">Jayle CP, Allain G, Ingrand P, Laksiri L, Bonnin E, Hajj-Chahine J, et al. Flail Chest in Polytraumatized Patients: Surgical Fixation Using Stracos Reduces Ventilator Time and Hospital Stay. Biomed Res Int. 2015;2015: 624723. PMID: 25710011 https://doi.org/10.1155/2015/624723</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Tanaka H, Yukioka T, Yamaguti Y, Shimizu S, Goto H, Matsuda H, et al. Surgical stabilization of internal pneumatic stabilization? A prospective randomized study of management of severe flail chest patients. J Trauma. 2002;52(4):727–732. PMID: 11956391 https://doi. org/10.1097/00005373-200204000-00020</mixed-citation><mixed-citation xml:lang="en">Tanaka H, Yukioka T, Yamaguti Y, Shimizu S, Goto H, Matsuda H, et al. Surgical stabilization of internal pneumatic stabilization? A prospective randomized study of management of severe flail chest patients. J Trauma. 2002;52(4):727–732. PMID: 11956391 https://doi. org/10.1097/00005373-200204000-00020</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Berthet J-P, Caro AG, Solovei L, Gilbert M, Bommart S, Gaudard P, et al. Titanium Implant Failure After Chest Wall Osteosynthesis. Ann Thorac Surg. 2015;99(6):1945–1952. PMID: 25916874 https://doi.org/10.1016/ j.athoracsur.2015.02.040</mixed-citation><mixed-citation xml:lang="en">Berthet J-P, Caro AG, Solovei L, Gilbert M, Bommart S, Gaudard P, et al. Titanium Implant Failure After Chest Wall Osteosynthesis. Ann Thorac Surg. 2015;99(6):1945–1952. PMID: 25916874 https://doi.org/10.1016/ j.athoracsur.2015.02.040</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Жестков К.Г., Барский Б.В., Воскресенский О.В. Мини-инвазивная хирургия в лечении флотирующих переломов ребер. Тихоокеанский медицинский журнал. 2006;1(23):62–66.</mixed-citation><mixed-citation xml:lang="en">Жестков К.Г., Барский Б.В., Воскресенский О.В. Мини-инвазивная хирургия в лечении флотирующих переломов ребер. Тихоокеанский медицинский журнал. 2006;1(23):62–66.</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Ke S, Duan H, Cai Y, Kang J, Feng Z. Thoracoscopy-Assisted Minimally Invasive Surgical Stabilization of the Anterolateral Flail Chest Using Nuss Bars. Ann Thorac Surg. 2014;97(6):2179–2182. PMID: 24882301 https://doi.org/10.1016/j.athoracsur.2013.08.066</mixed-citation><mixed-citation xml:lang="en">Ke S, Duan H, Cai Y, Kang J, Feng Z. Thoracoscopy-Assisted Minimally Invasive Surgical Stabilization of the Anterolateral Flail Chest Using Nuss Bars. Ann Thorac Surg. 2014;97(6):2179–2182. PMID: 24882301 https://doi.org/10.1016/j.athoracsur.2013.08.066</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Schots JP, Vissers YL, Hulsewé KW, Meesters B, Hustinx PA, Pijnenburg A, et al. Addition of video-assisted thoracoscopic surgery to the treatment of flail chest. Ann Thorac Surg. 2017;103(3):940–944. PMID: 27939010 https://doi.org/10.1016/j.athoracsur.2016.09.036</mixed-citation><mixed-citation xml:lang="en">Schots JP, Vissers YL, Hulsewé KW, Meesters B, Hustinx PA, Pijnenburg A, et al. Addition of video-assisted thoracoscopic surgery to the treatment of flail chest. Ann Thorac Surg. 2017;103(3):940–944. PMID: 27939010 https://doi.org/10.1016/j.athoracsur.2016.09.036</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Xia H, Zhu P, Li J, Zhu D, Sun Z, Deng L, et al. Thoracoscope combined with internal support system of chest wall in open reduction and internal fixation for multiple rib fractures. Exp Ther Med. 2018;16(6):4650–4654. PMID: 30542416 https://doi.org/10.3892/etm.2018.6817</mixed-citation><mixed-citation xml:lang="en">Xia H, Zhu P, Li J, Zhu D, Sun Z, Deng L, et al. Thoracoscope combined with internal support system of chest wall in open reduction and internal fixation for multiple rib fractures. Exp Ther Med. 2018;16(6):4650–4654. PMID: 30542416 https://doi.org/10.3892/etm.2018.6817</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Pieracci FM. Completely thoracoscopic surgical stabilization of rib fractures: can it be done and is it worth it? J Thorac Dis. 2019;11(Suppl 8): S1061–S1069. PMID: 31205763 https://doi.org/10.21037/jtd.2019.01.70</mixed-citation><mixed-citation xml:lang="en">Pieracci FM. Completely thoracoscopic surgical stabilization of rib fractures: can it be done and is it worth it? J Thorac Dis. 2019;11(Suppl 8): S1061–S1069. PMID: 31205763 https://doi.org/10.21037/jtd.2019.01.70</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Bauman ZM, Beard R, Cemaj S. When less is more: A minimally invasive, intrathoracic approach to surgical stabilization of rib fractures. Trauma Case Rep. 2021;32:100452. PMID: 33778146 https://doi.org/10.1016/ j.tcr.2021.100452</mixed-citation><mixed-citation xml:lang="en">Bauman ZM, Beard R, Cemaj S. When less is more: A minimally invasive, intrathoracic approach to surgical stabilization of rib fractures. Trauma Case Rep. 2021;32:100452. PMID: 33778146 https://doi.org/10.1016/ j.tcr.2021.100452</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Mayberry JC, Terhes JT, Ellis TJ, Wanek S, Mullins RJ. Absorbable plates for rib fracture repair: preliminary experience. J Trauma. 2003;55(5):835-839. PMID: 14608152 https://doi.org/10.1097/01. TA.0000090037.72142.33</mixed-citation><mixed-citation xml:lang="en">Mayberry JC, Terhes JT, Ellis TJ, Wanek S, Mullins RJ. Absorbable plates for rib fracture repair: preliminary experience. J Trauma. 2003;55(5):835-839. PMID: 14608152 https://doi.org/10.1097/01. TA.0000090037.72142.33</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Lafferty PM, Anavian J, Will RE, Cole PA. Operative treatment of chest wall injuries: indications, Technique,and outcomes. J Bone Joint Surg Am. 2011;93(1):97–110. PMID: 21209274 https://doi.org/10.2106/JBJS. I.00696</mixed-citation><mixed-citation xml:lang="en">Lafferty PM, Anavian J, Will RE, Cole PA. Operative treatment of chest wall injuries: indications, Technique,and outcomes. J Bone Joint Surg Am. 2011;93(1):97–110. PMID: 21209274 https://doi.org/10.2106/JBJS. I.00696</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Hollinger JO, Battistone GC. Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Orthop Relat Res. 1986;(207):290– 305. PMID: 3522015</mixed-citation><mixed-citation xml:lang="en">Hollinger JO, Battistone GC. Biodegradable bone repair materials. Synthetic polymers and ceramics. Clin Orthop Relat Res. 1986;(207):290– 305. PMID: 3522015</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
