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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23934/2223-9022-2022-11-4-708-717</article-id><article-id custom-type="elpub" pub-id-type="custom">nmp-1528</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Ранняя диагностика и лечение полиорганной недостаточности у больного с тяжелой сочетанной травмой</article-title><trans-title-group xml:lang="en"><trans-title>Prognosis, Early Diagnosis and Treatment of Multiple Organ Failure in a Patient With Severe Concomitant Trauma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7088-8645</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Владимирова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Vladimirova</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимирова Елизавета Семеновна, доктор медицинских наук, научный консультант отделения неотложной торакоабдоминальной хирургии </p><p>129010, Москва, Большая Сухаревская пл., 3</p><p> </p></bio><bio xml:lang="en"><p>Elizaveta S. Vladimirova, Doctor of Medical Sciences, Scientific Consultant, Scientific Department of Emergency Thoracic and Abdominal Surgery</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">prizma06@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2954-6985</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванов Павел Анатольевич, доктор медицинских наук, заведующий научным отделением сочетанной и множественной травмы </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Pavel A. Ivanov, Doctor of Medical Sciences, Head, Scientific Department of Concomitant and Multiple Trauma</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">ivanovpa@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3529-2344</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадыгов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Badigov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бадыгов Станислав Альбертович, заведующий отделением реанимации и интенсивной терапии для экстренных больных </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Stanislav A. Badigov, Head, Intensive Care Unit for Emergency Patients</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">badigovsa@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5798-1407</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попова Ирина Евгеньевна, кандидат медицинских наук, старший научный сотрудник отделения лучевой диагностики </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Irina E. Popova, Candidate of Medical Sciences, Senior Researcher, Department of Diagnostic Radiology</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">popovaie@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7802-2283</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рей</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Rey</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рей Сергей Игоревич, кандидат медицинских наук, старший научный сотрудник отделения неотложной хирургии, эндоскории и интенсивной терапии</p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Sergey I. Rey, Candidate of Medical Sciences, Senior Researcher, Department of Emergency Surgery, Endoscopy and Intensive Care</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">reysi@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1265-8032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеечкина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseechkina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеечкина Ольга Анатольевна, кандидат медицинских наук, старший научный сотрудник отделения лучевой диагностики </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Olga A. Alekseechkina, Candidate of Medical Sciences, Senior Researcher, Department of Diagnostic Radiology</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">alekseechkinaoa@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3726-3256</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердников</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdnikov</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бердников Геннадий Анатольевич, кандидат медицинских наук, старший научный сотрудник отделения неотложной хирургии, эндоскории и интенсивной терапии </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Gennady A. Berdnikov, Candidate of Medical Sciences, Senior Researcher, Department of Emergency Surgery, Endoscopy and Intensive Care</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">berdnikovga@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарабрин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarabrin</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарабрин Евгений Александрович, доктор медицинских наук, заведующий научным отделением неотложной торакоабдоминальной хирургии </p><p>129010, Москва, Большая Сухаревская пл., 3</p></bio><bio xml:lang="en"><p>Evgeny A. Tarabrin, Doctor of Medical Sciences, Head, Scientific Department of Emergency Thoracic and Abdominal Surgery</p><p>3 B. Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">tarabrinea@sklif.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГБУЗ «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ»<country>Россия</country></aff><aff xml:lang="en">N.V. Sklifosovsky Research Institute for Emergency Medicine<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>02</month><year>2023</year></pub-date><volume>11</volume><issue>4</issue><fpage>708</fpage><lpage>717</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Владимирова Е.С., Иванов П.А., Бадыгов С.А., Попова И.Е., Рей С.И., Алексеечкина О.А., Бердников Г.А., Тарабрин Е.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Владимирова Е.С., Иванов П.А., Бадыгов С.А., Попова И.Е., Рей С.И., Алексеечкина О.А., Бердников Г.А., Тарабрин Е.А.</copyright-holder><copyright-holder xml:lang="en">Vladimirova E.S., Ivanov P.A., Badigov S.A., Popova I.E., Rey S.I., Alekseechkina O.A., Berdnikov G.A., Tarabrin E.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/1528">https://www.jnmp.ru/jour/article/view/1528</self-uri><abstract><p>На примере клинического наблюдения показаны возможности динамической комплексной лучевой диагностики и клинико-лабораторных данных с учетом степени тяжести сочетанной травмы, которые позволяют отражать объективно динамику течения посттравматических изменений органов и тканей, дают возможность прогнозировать течение полиорганной недостаточности (ПОН). Последовательность и адекватный выбор тактики лечения с ранним использованием активных методов детоксикации способствуют благоприятному исходу.</p></abstract><trans-abstract xml:lang="en"><p>On the example of a clinical observation, we demonstrate the possibilities of dynamic multimodality imaging techniques and clinical and laboratory data, taking into account the severity of the concomitant trauma, which allow us to reflect objectively the dynamics of post-traumatic changes in the organs and tissues and predict the course of multiple organ failure (MOF). Consistency and adequate choice of treatment tactics with early use of active detoxification methods contribute to a favorable outcome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сочетанная травма</kwd><kwd>лечение</kwd><kwd>осложнения</kwd><kwd>ПОН</kwd><kwd>лучевые методы диагностики ( рентгенография)</kwd><kwd>компьютерная томография (КТ)</kwd><kwd>лабораторные методы</kwd><kwd>ультразвуковое исследование (УЗИ)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>concomitant trauma</kwd><kwd>treatment</kwd><kwd>complications</kwd><kwd>MOF</kwd><kwd>diagnostic radiology (radiography)</kwd><kwd>computed tomography</kwd><kwd>laboratory methods</kwd><kwd>ultrasound examination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hildebrand F, Pape H-C, Krettek C. Die Bedeutung der Zytokine in der posttraumatischen Entzündungsreaktion. Unfallchirurg. 2005;108(10):793–803. 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