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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23934/2223-9022-2022-11-3-412-418</article-id><article-id custom-type="elpub" pub-id-type="custom">nmp-1442</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Прогноз результата кожной пластики по параметрам микроциркуляции в ожоговой ране</article-title><trans-title-group xml:lang="en"><trans-title>Estimation of Microcirculation Parameters in a Burn Wound for Prediction of Skin Grafting Outcomes After Tangential Necrectomy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2493-5498</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиновьев</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinoviev</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зиновьев Евгений Владимирович доктор медицинских наук, профессор, руководитель отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Evgeny V. Zinoviev Doctor of Medical Sciences, Professor, Head, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">evz@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5800-5803</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солошенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Soloshenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Солошенко Виталий Викторович доктор медицинских наук, доцент, врач-хирург отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Vitaly V. Soloshenko Doctor of Medical Sciences, Associate Professor, Surgeon, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">burncenter.vs@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5687-7168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костяков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostyakov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Костяков Денис Валерьевич кандидат медицинских наук, научный сотрудник отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Denis V. Kostyakov Candidate of Medical Sciences, Researcher, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">kosdv@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гогохия</surname><given-names>Т. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Gogokhia</surname><given-names>T. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гогохия Тамара Зауровна врач-хирург отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Tamara Z. Gogokhia Surgeon, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">tamargogokhia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коуров</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kourov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коуров Антон Сергеевич врач-хирург отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Anton S. Kourov Surgeon, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">anton.kourov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3096-0008</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пятаков</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pyatakov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пятаков Станислав Николаевич кандидат медицинских наук, врач-хирург отдела термических поражений</p><p>192242, Санкт-Петербург, Будапештская ул., д. 3, лит. А</p></bio><bio xml:lang="en"><p>Stanislav N. Pyatakov Candidate of Medical Sciences, Surgeon, Department of Thermal Injuries</p><p>192242, St. Petersburg, Budapeshtskaya str., 3, lit. A</p></bio><email xlink:type="simple">spyatakov@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГБУ «Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе»<country>Россия</country></aff><aff xml:lang="en">Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2022</year></pub-date><volume>11</volume><issue>3</issue><fpage>412</fpage><lpage>418</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зиновьев Е.В., Солошенко В.В., Костяков Д.В., Гогохия Т.З., Коуров А.С., Пятаков С.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Зиновьев Е.В., Солошенко В.В., Костяков Д.В., Гогохия Т.З., Коуров А.С., Пятаков С.Н.</copyright-holder><copyright-holder xml:lang="en">Zinoviev E.V., Soloshenko V.V., Kostyakov D.V., Gogokhia T.Z., Kourov A.S., Pyatakov S.N.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/1442">https://www.jnmp.ru/jour/article/view/1442</self-uri><abstract><p>Актуальность Неравномерность и мозаичность по глубине ожогового поражения кожи ограничивает возможности выполнения прецизионной тангенциальной некрэктомии в ранние сроки после травмы. Нерадикальная некрэктомия приводит к лизису пересаженных аутодермотрансплантатов. Наиболее актуальна данная проблема в лечении пострадавших с обширными дермальными и глубокими ожогами.Цель Изучить зависимость между параметрами микроциркуляции в ожоговой ране и результатами аутодермотрансплантации после выполнения тангенциальной некрэктомии.Материал и методы Хирургическое лечение 74 пациентов с обширными ожогами кожи, включенных в исследование, осуществляли путем тангенциальной некрэктомии с одновременной аутодермотрансплантацией. Все операции выполняли в ранние сроки (до 10 суток) после травмы до формирования линии демаркации. Параметры микроциркуляции в ожоговой ране изучали методом лазерной допплеровской флоуметрии до и после тангенциальной некрэктомии и в здоровой коже той же анатомической области.Результаты Выявлены статистически значимые различия (при p≤0,001) между параметрами микроциркуляции непосредственно в ожоговой ране после выполнения тангенциальной некрэктомии и на контрольном участке неповрежденной кожи. В этом случае результаты аутодермотрансплантации характеризовались частотой приживления кожи до 60–70%. В тех областях тела, где различий между показателями микроциркуляции не было, результаты приживления превысили 80%.Выводы Оценка микроциркуляции методом лазерной допплеровской флоуметрии может явиться достоверным методом диагностики состояния и жизнеспособности ожоговой раны после тангенциального иссечения погибших тканей в ранние сроки лечения – до формирования демаркационной линии. Методика диагностики проста в применении, однако требует навыков работы с флуометром, унификации таких приборов и методик их использования в практике хирургического лечения ожогов.</p></abstract><trans-abstract xml:lang="en"><p>BACKGROUND Irregularity and mosaicity in the depth of the burn skin lesion limits the possibility of performing precision tangential necrectomy in the early stages after injury. Non-radical necrectomy leads to lysis of transplanted autodermal grafts. This problem is most relevant in the treatment of victims with extensive dermal and deep burns.AIM OF STUDY To study the relationship between microcirculation parameters in the burn wound and the outcomes of autodermal transplantation after tangential necrectomy.MATERIAL AND METHODS 74 patients with extensive skin burns included in the study underwent tangential necrectomy with simultaneous autodermal transplantation. All operations were performed early (up to 10 days) after injury before the formation of the demarcation line. Microcirculation parameters in the burn wound were studied by laser Doppler flowmetry before and after tangential necrectomy and in healthy skin of the same anatomical region.RESULTS Statistically significant differences (p≤0.001) were found between microcirculation parameters in the center of the burn wound after tangential necrectomy and in the control area of intact skin. In this case, the results of autodermal transplantation were characterized by a skin engraftment rate of up to 60–70%. In those areas of the body where there were no differences between microcirculation parameters , the engraftment exceeded 80%.CONCLUSION Assessment of microcirculation by laser Doppler flowmetry can be a reliable method for diagnosing the condition and viability of a burn wound after tangential excision of dead tissues in the early stages of treatment — before the formation of a demarcation line. The diagnostic technique is easy to use, but requires skills in working with a flowmeter, unification of such devices and methods for their use in the practice of surgical treatment of burns.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожоги</kwd><kwd>тангенциальная некрэктомия</kwd><kwd>аутодермотрансплантация</kwd><kwd>лазерная допплеровская флоуметрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>burns</kwd><kwd>tangential necrectomy</kwd><kwd>autodermal transplantation</kwd><kwd>laser doppler flowmetry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Хирургическое лечение пострадавших от ожогов: клинические рекомендации. Москва, 2015. 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