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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nmp</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Sklifosovsky Journal "Emergency Medical Care"</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-9022</issn><issn pub-type="epub">2541-8017</issn><publisher><publisher-name>“N.V. Sklifosovsky Research Institute for Emergency Medicine”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23934/2223-9022-2022-11-1-137-146</article-id><article-id custom-type="elpub" pub-id-type="custom">nmp-1348</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Распространенный аппендикулярный перитонит: лапароскопический или открытый доступ — критический анализ</article-title><trans-title-group xml:lang="en"><trans-title>Diffuse Appendicular Peritonitis: Laparoscopic vs Open Access — Viewpoint From Aside</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8522-9792</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнян</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunyan</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Арутюнян Анжелика Сергеевна - младший научный сотрудник отделения неотложной хирургии, эндоскопии и интенсивной терапии ГБУЗ «НИИ СП им. Н.В. Склифосовского ДЗМ».</p><p>123242, Москва, ул. Баррикадная, д. 2/1, стр. 1; 129090, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Anzhelika S. Arutyunyan - Junior Researcher of the Department of  Emergency Surgery, Endoscopy and Intensive Therapy.</p><p>2/1 b. 1 Barrikadnaya Str., Moscow, 123242; 3 B. Sukharevskaya Square, Moscow, 107045</p></bio><email xlink:type="simple">moiseiyshkaa@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5724-6034</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Благовестнов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Blagovestnov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Благовестнов Дмитрий Алексеевич - доктор медицинских наук, профессор, заведующий кафедрой неотложной и общей хирургии имени профессора А.С. Ермолова ФГБОУ ДПО РМАНПО МЗ РФ.</p><p>123242, Москва, ул. Баррикадная, д. 2/1, стр. 1; 129090, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Dmitry A. Blagovestnov - Doctor of Medical Sciences, Professor, Head of the Department of Emergency and General Surgery named after Professor A.S. Ermolov.</p><p>2/1 b. 1 Barrikadnaya Str., Moscow, 123242; 3 B. Sukharevskaya Square, Moscow, 107045</p></bio><email xlink:type="simple">sklifkafedra@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1100-486X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левитский</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Levitsky</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левитский Владислав Дмитриевич - кандидат медицинских наук, ведущий научный сотрудник отделения неотложной хирургии, эндоскопии и интенсивной терапии ГБУЗ «НИИ СП им. Н.В. Склифосовского ДЗМ».</p><p>129090, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Vladislav D. Levitsky - Candidate of Medical Sciences, Leading Researcher of the Department of  Emergency Surgery, Endoscopy and Intensive Therapy.</p><p>3 B. Sukharevskaya Square, Moscow, 107045</p></bio><email xlink:type="simple">vdlevitsky@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1270-5414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярцев</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yartsev</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ярцев Петр Андреевич - доктор медицинских наук, профессор, заведующий научным отделением неотложной хирургии, эндоскопии и интенсивной терапии ГБУЗ «НИИ СП им. Н.В. Склифосовского ДЗМ».</p><p>123242, Москва, ул. Баррикадная, д. 2/1, стр. 1; 129090, Москва, Большая Сухаревская пл., д. 3; 440066, Пенза, ул. Стасова, д. 8А</p></bio><bio xml:lang="en"><p>Peter A. Yartsev - Doctor of Medical Sciences, Professor, Head of the Scientiﬁ c Department of  Emergency Surgery, Endoscopy and Intensive Therapy.</p><p>2/1 b. 1 Barrikadnaya Str., Moscow, 123242; 3 B. Sukharevskaya Square, Moscow, 107045; 8A Stasov Str., Penza, 440066</p></bio><email xlink:type="simple">peter-yartsev@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования МЗ РФ; ГБУЗ Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education; N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования МЗ РФ; ГБУЗ Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского ДЗМ; Пензенский институт усовершенствования врачей — филиал ФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education; N.V. Sklifosovsky Research Institute for Emergency Medicine; Penza Institute for Advanced Doctors Training, the branch of the Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>08</day><month>04</month><year>2022</year></pub-date><volume>11</volume><issue>1</issue><fpage>137</fpage><lpage>146</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арутюнян А.С., Благовестнов Д.А., Левитский В.Д., Ярцев П.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Арутюнян А.С., Благовестнов Д.А., Левитский В.Д., Ярцев П.А.</copyright-holder><copyright-holder xml:lang="en">Arutyunyan A.S., Blagovestnov D.A., Levitsky V.D., Yartsev P.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jnmp.ru/jour/article/view/1348">https://www.jnmp.ru/jour/article/view/1348</self-uri><abstract><p>Острый аппендицит является наиболее распространенным острым хирургическим заболеванием и, несмотря на то что имеется значительное сокращение его доли в практике врача-хирурга (40,3% — 2000, 24,8% — 2019), он все равно занимает первое место по встречаемости и оперативной активности.</p><p>Перфоративная форма острого аппендицита с развитием распространенного перитонита увеличивает частоту послеоперационных осложнений до 47%, а летальность — до 3%. Летальность в случае развития разлитого гнойного перитонита составляет 4,5–58%, а при тяжелых формах распространенного перитонита с развитием инфекционно-токсического шока и полиорганной недостаточности может превышать 70%.</p><p>Национальные клинические рекомендации при остром аппендиците с распространенным перитонитом допускают выполнение аппендэктомии как из срединного, так и из лапароскопического доступа при отсутствии общих противопоказаний к созданию пневмоперитонеума. Однако несмотря на доказанные преимущества лапароскопической аппендэктомии, имеются противники ее использования при распространенных формах аппендикулярного перитонита.</p><p>В литературе отмечено увеличение количества послеоперационных абсцессов при минимально инвазивном доступе, однако последние рандромизированные исследования опровергают данный факт. Также имеются данные, что лапароскопический метод при аппендикулярном перитоните часто приводит к удлинению времени операции и более высоким операционным затратам, но при этом происходит уменьшение болевого послеоперационного синдрома, сокращение сроков стационарного лечения и ранняя социально-трудовая реабилитация, что приводит к общему снижению расходов больницы.</p><p>Таким образом, на сегодняшний день нет общепринятого мнения о целесообразности лапаро­скопического доступа при аппендикулярном перитоните. На данный момент наиболее частая интраоперационная причина отказа от минимально инвазивного метода хирургического лечения — наличие распространенного перитонита. Однако прослеживается тенденция к попытке стандартизировать показания и противопоказания, что и явилось целью нашего литературного обзора.</p></abstract><trans-abstract xml:lang="en"><p>The perforative acute appendicitis with the development of diffuse peritonitis increases the incidence of postoperative complications to 47%, and mortality to 3%. Mortality in the case of the development of diffuse purulent peritonitis makes 4.5-58%, and it can exceed 70% in severe forms of diffuse peritonitis with the development of infectious-toxic shock and multiple organ failure. National Clinical Guidelines for acute appendicitis with diffuse peritonitis allow for appendectomy from both the median and laparoscopic access in the absence of general contraindications to the creation of pneumoperitoneum. However, despite the proven advantages of laparoscopic appendectomy, there are opponents of its use in diffuse forms of appendicular peritonitis. An increased number of postoperative abscesses with a minimally invasive approach has been reported in literature; however, recent randomized studies refute this fact. There is also evidence that the laparoscopic method for appendicular peritonitis often leads to a lengthening of the operation time and higher operating costs, but at the same time there is a decrease in postoperative pain syndrome, a reduction in the length of inpatient treatment and early social and labor rehabilitation, which leads to an overall decrease in hospital costs. Thus, to date, there is no generally accepted opinion about the advisability of laparoscopic access for appendicular peritonitis. At the moment, the presence of diffuse peritonitis is the most common intraoperative reason for refusing a minimally invasive surgical treatment. However, there is a tendency to trying to standardize indications and contraindications, which was the objective of our literature review.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лапароскопия</kwd><kwd>аппендикулярный перитонит</kwd><kwd>перитонеальный лаваж</kwd><kwd>антибиотикотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>laparoscopy</kwd><kwd>appendicular peritonitis</kwd><kwd>peritoneal lavage</kwd><kwd>antibiotic therapy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование не имеет спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The study has no sponsorship</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гуляев А.А., Ермолов А.С., Затевахин И.И., Ивахов Г.Б., Кириенко А.И., Луцевич О.Э., и др. (сост.); Российское общество хирургов. Острый аппендицит у взрослых. 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